Results 231 to 240 of about 14,463,930 (343)

Adaptive Non-Singular Fast Terminal Sliding Mode Trajectory Tracking Control for Robotic Manipulator with Novel Configuration Based on TD3 Deep Reinforcement Learning and Nonlinear Disturbance Observer. [PDF]

Sensors (Basel)
You H, Liu Y, Shi Z, Wang Z, Wang L, Xue G.   +5 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Building an implementation framework for directly observed feedback by attending physicians. [PDF]

PLoS One
Raikhel AV, Starks H, Berger G, Redinger J.   +3 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Modeling human visuomotor adaptation with a disturbance observer framework. [PDF]

PLoS Comput Biol
Sharma G, 't Hart BM, Orban de Xivry JJ, Henriques DYP, Broucke ME.   +4 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

An AC voltage sensorless predictive current control method for grid-tied inverter with enhanced robustness against current DC offset. [PDF]

Sci Rep
Zhang G, Dong W, Meng L, Li J, Wang J.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Intra- and inter-observer reliability of ultrasound muscle thickness of gluteal and biceps femoris long head in individuals with and without SCI. [PDF]

Clin Physiol Funct Imaging
Wijker BJ, de Groot S, Denneman B, Brouwer P, Tomaras V, Haarler A, Weide G, Mokkink LB, van Dongen JM, Janssen TWJ.   +9 more
europepmc   +1 more source