Results 91 to 100 of about 263,310 (323)
Review of: "Observers as Agents: Relational Epistemology from Physics to Ecology" [PDF]
Fernando José García Selgas
+8 more sources
Quantum Physics and the Existence of God
ReligionsInterpretations of quantum physics are shown to presuppose the reality of consciousness. But if a minimal realism about the external world is true, then the consciousness presupposed by quantum reality cannot be only that of the scientific observer ...
Stephen Priest
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
The importance of the observer in science
, 2005 The concept of {\em complexity} (as a quantity) has been plagued by numerous contradictory and confusing definitions. By explicitly recognising a role for the observer of a system, an observer that attaches meaning to data about the system, these ...
Standish, Russell K.
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Gravitational interactions with information dynamics
Frontiers in Astronomy and Space SciencesIntroductionUnifying gravity with quantum mechanics remains a cornerstone challenge in physics, with information theory providing a transformative perspective through concepts like the holographic principle and entropic gravity.MethodsWe derive an ...
Mahgoub A. Salih
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Workshop on the evolution of the Martian atmosphere [PDF]
Thirty-three papers based on the state of our knowledge prior to the anticipated new results from Mars Observer were presented at the workshop. Because of the nature of the subject, the scope of the papers covered a broad disciplinary range encompassing ...
Jakosky, B. M., Luhmann, J. G.
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source