Results 111 to 120 of about 1,578,105 (322)
Medical Physics (Lancaster), 2017 Purpose: Model observers have been successfully developed and used to assess the quality of static 2D CT images. However, radiologists typically read images by paging through multiple 2D slices (i.e., multislice reading). The purpose of this study was to
Lifeng Yu +6 more
semanticscholar +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Workshop on the evolution of the Martian atmosphere [PDF]
Thirty-three papers based on the state of our knowledge prior to the anticipated new results from Mars Observer were presented at the workshop. Because of the nature of the subject, the scope of the papers covered a broad disciplinary range encompassing ...
Jakosky, B. M., Luhmann, J. G.
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The importance of the observer in science
, 2005 The concept of {\em complexity} (as a quantity) has been plagued by numerous contradictory and confusing definitions. By explicitly recognising a role for the observer of a system, an observer that attaches meaning to data about the system, these ...
Standish, Russell K.
core +1 more source
Observing human interaction with physical devices [PDF]
Experimental Brain Research, 2009 Previous study has shown that if we observe another person operating a tool or physical device, then the action rule of the observed action is automatically activated and can subsequently facilitate own actions. In this study, the mechanisms responsible for this automatic priming of actions are investigated.
openaire +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Quantum Physics and the Existence of God
ReligionsInterpretations of quantum physics are shown to presuppose the reality of consciousness. But if a minimal realism about the external world is true, then the consciousness presupposed by quantum reality cannot be only that of the scientific observer ...
Stephen Priest
doaj +1 more source
The Problem of the Observer in Physics
, 2010 This paper has been withdrawn by the author. In this short paper I present a new approach to the problem of measurement, based on the difference between language (reality) and meta-language (meta-reality). This way, it will be shown as the measurement is a meta-sentence on a real event.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source