Results 131 to 140 of about 1,578,105 (322)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Towards Relational Foundations for Spacetime Quantum Physics

open access: yesUniverse
Rovelli’s relational interpretation of quantum mechanics tells us that the description of a system in the formalism of quantum mechanics is not an absolute but is relative to the observer itself.
Pietro Dall’Olio, José A. Zapata
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A Non-Stochastic Special Model of Risk Based on Radon Transform

open access: yesEntropy
The concept of risk is fundamental in various scientific fields, including physics, biology and engineering, and is crucial for the study of complex systems, especially financial markets.
Marcin Makowski, Edward W. Piotrowski
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A New Proposal of Quantum Theory of Soul Based on Tao Science

open access: yesReports in Advances of Physical Sciences
The scientific study of the soul has garnered increased attention but remains limited in progress. We propose to give the soul a scientific definition and use quantum physics to predict its character, qualities and behavior.
Zhi Gang Sha, Rulin Xiu
doaj   +1 more source

Cosmological networks

open access: yesNew Journal of Physics, 2014
Networks often represent systems that do not have a long history of study in traditional fields of physics; albeit, there are some notable exceptions, such as energy landscapes and quantum gravity.
Marián Boguñá   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

On observers in holographic maps

open access: yesJournal of High Energy Physics
A straightforward gravitational path integral calculation implies that closed universes are trivial, described by a one dimensional Hilbert space. Two recent papers by Harlow-Usatyuk-Zhao and Abdalla-Antonini-Iliesiu-Levine have sought to ameliorate this
Chris Akers   +5 more
doaj   +1 more source

The Observer Is, by Necessity, the Complete Foundation to Physics

open access: yes, 2021
While there exist in the wild a process to derive the laws of physics ---namely, the practice of science--- it has never been completely formalized within mathematics. Here, we understand this lack as an unrealized opportunity to source the foundations of physics while remaining mathematically precise.
openaire   +1 more source

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