Results 91 to 100 of about 3,729,343 (335)
Foot & Ankle Orthopaedics, 2018 Category: Trauma Introduction/Purpose: Objective: To perform an independent inter-observer and intra-observer agreement assessment of the new pilon fracture classification system based on CT-scan.
Joaquin Palma MD +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Sidney Machine Tool Company lathe photograph
This photograph shows a lathe at the Sidney Machine Tool Company. Sidney Tool Company was founded in 1905 by Alfred C. Getz in Sidney, Ohio. Getz was also acting plant manager for Monarch Machine Tool, also in Sidney, during the same time.
Sidney Machine Tool Company
core +2 more sources
Assessment and Observation: The Anaesthetist's Tools [PDF]
Anaesthesia and Intensive Care, 2008 C, Ball, R N, Westhorpe
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Development and validation of a rapid test kit for iodine detection in salt
Italian Journal of Food SafetyIodine deficiency disorders are widespread among vulnerable populations in Pakistan. To combat this menace, the Universal Salt Iodization program needs regular monitoring throughout the salt supply chain.
Tauqeer Ahmad
doaj +1 more source
Journal of Foot and Ankle Research, 2019 Background We aimed to develop and evaluate a tool for clubfoot therapists in low resource settings to assess the results of Ponseti treatment of congenital talipes equinovarus, or clubfoot, in children of walking age.
Tracey Smythe +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source