Results 111 to 120 of about 99,486 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Comparison of intra- and inter-observer variability of the speckle tracking parameters by the coefficient of variation and intraclass-correlation coefficient.

, 2014
Presented are median and interquartile range; statistical significance after Bonferroni correction for ...
Gerd Schmalisch (320665), Lothar Schmitz (624997), Stefanie Rhode (320659), Christoph Bührer (65653), Christoph Czernik (320657), Sven Helfer (624996)   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Intra-observer reproducibility.

, 2019
The graph shows interclass correlation coefficients (ICC) and coefficients of variation (CoV) for intra-observer reproducibility prior to and after training. LV/RV: left/right ventricle, GLS: global longitudinal strain, GCS: global circumferential strain,
Marcus Billing (6264023), Tomas Lapinskas (6264029), Georg Metschies (6264020), Burkert Pieske (790365), Boris Bigalke (320339), Andreas Schuster (329436), Roman J. Gertz (6264026), Sebastian Kelle (114520), Johannes T. Kowallick (640418), Joachim Lotz (640425), Philipp Beerbaum (718508), Sören J. Backhaus (6264017), Gerd Hasenfuß (326792), Shelby Kutty (294553)   +13 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Bosniak classification system:inter-observer and intra-observer agreement among experienced uroradiologists

, 2015
BACKGROUND: The Bosniak classification is a diagnostic tool for the differentiation of cystic changes in the kidney. The process of categorizing renal cysts may be challenging, involving a series of decisions that may affect the final diagnosis and ...
Karstoft, Jens, Hørlyck, Arne, Osther, Palle Js; id_orcid, Graumann, Ole, Osther, Susanne S   +4 more
core   +1 more source

The impact of inter-observer variation in delineation on robustness of radiomics features in non-small cell lung cancer. [PDF]

Sci Rep, 2022
Kothari G, Woon B, Patrick CJ, Korte J, Wee L, Hanna GG, Kron T, Hardcastle N, Siva S.   +8 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Distribution of samples in the test subset for inter-observer variation.

Distribution of samples in the test subset for inter-observer variation.
Mahnaz Mohammadi (14209860), David Harris-Birtill (4521286), Gareth Bryson (14761877), Prakash Konanahalli (14761874), Sarah Bell (3360230), Ognjen Arandjelović (295373), Christina Fell (14209857), David Morrison (77661), Sheeba Syed (14761871), David J. Harrison (171106)   +9 more
core   +1 more source

Inter-observer reproducibility.

, 2019
The graph shows interclass correlation coefficients (ICC) and coefficients of variation (CoV) for inter-observer reproducibility prior to and after training. LV/RV: left/right ventricle, GLS: global longitudinal strain, GCS: global circumferential strain,
Marcus Billing (6264023), Tomas Lapinskas (6264029), Georg Metschies (6264020), Burkert Pieske (790365), Boris Bigalke (320339), Andreas Schuster (329436), Roman J. Gertz (6264026), Sebastian Kelle (114520), Johannes T. Kowallick (640418), Joachim Lotz (640425), Philipp Beerbaum (718508), Sören J. Backhaus (6264017), Gerd Hasenfuß (326792), Shelby Kutty (294553)   +13 more
core   +1 more source