Results 141 to 150 of about 99,486 (307)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Observer variation in histological assessment of Helicobacter pylori on gastric biopsies [6]

, 1996
Observer variation in histological assessment of Helicobacter pylori on gastric ...
Santucci R., Paganelli G. M., Terranova A., Amorosi A., Vaira D., Biasco G., Pileri S., Renga M.   +7 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Online studies on variation in orthopedic surgery: computed tomography in MPEG4 versus DICOM format

, 2017
The purpose of this study was to compare the observer participation and satisfaction as well as interobserver reliability between two online platforms, Science of Variation Group (SOVG) and Traumaplatform Study Collaborative, for the evaluation of ...
van Dijk, C Niek, Science of Variation Group, Traumaplatform Study Collaborative, Mellema, Jos J, Mallee, Wouter H, Guitton, Thierry G, Doornberg, Job N, Ring, David   +7 more
core   +1 more source

A novel Sensorless Control Strategy Based on Sliding Mode Observer for Non-Sinusoidal Seven-phase PMSM [PDF]

, 2020
This paper proposes a new sensorless control strategy based on a Sliding Mode Observer (SMO) for a non-sinusoidal seven phase PMSMs. This strategy, based on all harmonics contained in the back-EMF, is compared to the classical sensorless control strategy
NGUYEN, Ngac Ky, MINI, Youssouf, SEMAIL, Eric, NGUYEN, Ngacky   +3 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Observer variation in chest radiography of acute lower respiratory infections in children: a systematic review

, 2001
Background Knowledge of the accuracy of chest radiograph findings in acute lower respiratory infection in children is important when making clinical decisions.
Swingler George H, Swingler, George H, George H Swingler   +2 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Transformer-Based HER2 Scoring in Breast Cancer: Comparative Performance of a Foundation and a Lightweight Model

Diagnostics
Background/Objectives: Human epidermal growth factor 2 (HER2) scoring is critical for modern breast cancer therapies, especially with emerging indications of antibody–drug conjugates for HER2-low tumors.
Yeh-Han Wang, Min-Hsiang Chang, Hsin-Hsiu Tsai, Chun-Jui Chien, Jian-Chiao Wang   +4 more
doaj   +1 more source