Results 151 to 160 of about 99,486 (307)
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Observer design for switching nonlinear systems
International audienceIn this paper we consider observer design for discrete-time switching systems represented by Takagi-Sugeno fuzzy models. For the design we use a switching Lyapunov function defined on the switches.
Lendek, Zsofia +7 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Inter- and Intra-Observer Reliability of Skinfold Thickness Measurements in Newborn Infants
Inter-observer and intra-observer reliability in obtaining skinfold thickness measurements on newborn infants were examined. As part of ongoing growth studies,20 duplicate sets of eight skinfolds were measured by an index observer and one of three other ...
Thies, Cole +4 more
core
Low intensity heart murmurs in boxer dogs: inter-observer variation and effects of stress testing
Inter-observer variation in the detection and grading of low intensity heart murmurs in boxer dogs was investigated. Six veterinarians with different levels of experience examined 27 boxers by cardiac auscultation.
J. Dukes‐McEwan +13 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Effect of Inter-Observer Variation on the Association between Contamination Hazards and the Microbiological Quality of Water Sources: A Longitudinal Study. [PDF]
Okotto-Okotto J +6 more
europepmc +1 more source
Observations on Phonological Variation in Kera’a
AbstractKera’a (clk, idum1241, ‘Idu’) is a Tibeto-Burman language spoken by around 12,000 Idu Mishmi living in Lower Dibang Valley and Dibang Valley, Arunachal Pradesh. The language is currently threatened (EGIDS 6b), but will likely become endangered due to the disruption of intergenerational transmission.
openaire +1 more source

