Correcting gene expression data when neither the unwanted variation nor the factor of interest are observed [PDF]
When dealing with large scale gene expression studies, observations are commonly contaminated by unwanted variation factors such as platforms or batches. Not taking this unwanted variation into account when analyzing the data can lead to spurious associations and to missing important signals. When the analysis is unsupervised, e.g., when the goal is to
arxiv
Observer Error and Variation in the Interpretation of Electrocardiograms in an Epidemiological Study of Coronary Heart Disease [PDF]
R. M. Acheson
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Locating hyperfunctioning parathyroid glands using 11C-Choline PET/CT: an inter- and intra-observer variation study. [PDF]
Christensen JW+10 more
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Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Inter-Observer Variation in Delineating the Pharyngeal Constrictor Muscle as Organ at Risk in Radiotherapy for Head and Neck Cancer. [PDF]
Petkar I+5 more
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Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
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Radiological Signs of Ulcerative Colitis as Sessment of Their Reliability by Means of Observer Variation Studies [PDF]
N. Geffan+4 more
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Comparing intra-observer variation and external variations of a fully automated cephalometric analysis with a cascade convolutional neural net. [PDF]
Kim IH, Kim YG, Kim S, Park JW, Kim N.
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Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston+7 more
wiley +1 more source
Reliability of the interpretation of coronary angiography by the simple visual method
OBJECTIVE: Evaluation of inter and intraobserver reproducibility of by the visual method interpretation of cineangiogram in a clinically based context. METHODS: Five interventional cardiologists analyzed 11 segments of 8 coronary cineangiograms at a two ...
Guimarães Jorge Augusto Nunes+5 more
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