Results 181 to 190 of about 516,287 (323)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Inter-Observer Variation in the Pathologic Identification of Extranodal Extension in Nodal Metastasis from Papillary Thyroid Carcinoma [PDF]

, 2016
Eugenie Du, Bruce M. Wenig, Henry K. Su, Meghan E. Rowe, Grace C. Haser, L. Sylvia, Zubair Baloch, William C. Faquin, Giovanni Fellegara, Thomas J. Giordano, Ronald Ghossein, Virginia A. LiVolsi, Ricardo V. Lloyd, Özgür Mete, Umut Özbek, Juan Rosaí, Saul Suster, Lester D.�R. Thompson, Andrew T. Turk, Mark L. Urken   +19 more
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Inter- and intra-observer variation in phytolith morphometry. [PDF]

Ann Bot
Out WA, Evett R, Hošková K, Power RC, Ruiz-Pérez J, Tromp M, Vrydaghs L, Wade K, Hasler M.   +8 more
europepmc   +1 more source

HRCT diagnosis of diffuse parenchymal lung disease: inter-observer variation

, 2004
Z. Aziz
openalex   +1 more source

The Analysis of the Observations of the Variation of Latitude [PDF]

Monthly Notices of the Royal Astronomical Society, 1955
Andrew J. Young, A. M. Walker
openaire   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Changes in inter observer variation of Schatzker and AO/OTA classification of tibial plateau fractures on addition of CT scan. [PDF]

Int J Burns Trauma
Narang HS, Srivastava A, Aggarwal AN, Chadha M, Tandon A, Rathod SB.   +5 more
europepmc   +1 more source

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation [PDF]

, 2018
Fabian Bartel, Marcel van Herk, Hugo Vrenken, F. Vandaele, Stefan Sunaert, Katrien De Jaeger, N. J. Dollekamp, C. Carbaat, Emmy Lamers, Edith Dieleman, Yolande Lievens, Dirk De Ruysscher, S. B. Schagen, M. B. de Ruiter, Jan C. de Munck, J. Belderbos   +15 more
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source