Results 251 to 260 of about 99,486 (307)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Intra- and inter-observer reliability of ultrasound muscle thickness of gluteal and biceps femoris long head in individuals with and without SCI. [PDF]

Clin Physiol Funct Imaging
Wijker BJ, de Groot S, Denneman B, Brouwer P, Tomaras V, Haarler A, Weide G, Mokkink LB, van Dongen JM, Janssen TWJ.   +9 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Evaluation of Interexaminer Reliability in Visual Shade Matching: A Comparative Analysis of Optilume Trueshade and Conventional Lighting for Permanent Anterior Teeth. [PDF]

Cureus
Alkhalifah OF, Ali Shah S, Tareen SUK, Ahmad MZ.   +3 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Evaluation of Reproducibility and Accuracy of Facial Soft Tissue Landmarks in Individuals Assessed Using Various 3D Face Scanning Modalities: A Systematic Review. [PDF]

Cureus
Naikwadi S, Powar S, Bhad W, Ghonmode S, Bj A, Kadhare S.   +5 more
europepmc   +1 more source

First abundance estimate for greater Caribbean manatees (Trichechus Manatus Manatus) in Belize. [PDF]

Sci Rep
Edwards HH, Moore JF, Gomez NA, Galves JA, Valentine A, Galves CG, Ubeda AJ, Álvarez-Alemán A.   +7 more
europepmc   +1 more source

Skin involvement is measurable in Dupuytrens' disease: Reliability of standardized skin elasticity measurements with Cutometer® MPA 580. [PDF]

Hand Ther
Meulyzer C, Tulkens P, Van den Kerckhove E, Van Nuffel M, Anthonissen M, Degreef I.   +5 more
europepmc   +1 more source

Position-Induced Change in Carotid Corrected Flow Time Predicts Spinal Hypotension in Cesarean Delivery. [PDF]

Int J Womens Health
Hao S, Cao Y, Zhang T, Cao Y, Wang Y.
europepmc   +1 more source

Left and right ventricular strain-volume/area loops: an evaluation of intra-observer, inter-observer, and test-retest reliability. [PDF]

Eur Heart J Imaging Methods Pract
Donker SCM, Maxwell JD, Haibe HJ, Verhoeven ECC, Kerstens TP, Buckley BJR, Thijssen DHJ, Oxborough D.   +7 more
europepmc   +1 more source