Results 131 to 140 of about 25,432,868 (344)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Establishment and discontinuance criteria for automated weather observing systems (AWOS) [PDF]

open access: yes
This report develops establishment and discontinuance criteria for automatedweather observing systems (AWOS) for publication in FAA Order 703l.2B, AirwayPlanning Standard Number One.
Keech, Ward L.   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Applying OGC sensor web enablement to ocean observing systems [PDF]

open access: yes, 2016
The complexity of marine installations for ocean observing systems has grown significantly in recent years. In a network consisting of tens, hundreds or thousands of marine instruments, manual configuration and integration becomes very challenging ...
Jirka, Simon   +6 more
core   +1 more source

Cybernetics of Observing Systems and Lonergan's Generalized Empirical Method [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2019
Cybernetics is inherently interdisciplinary and reflexive; second-order cybernetics stresses reflective interaction of knowledge and action with the observer.
Fr. Joseph R. Laracy   +3 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Niklas Luhmann, Observing Systems and Social Critique [PDF]

open access: yes, 2014
This article on the theories of the German sociologist Niklas Luhmann starts with a discussion of the formal codes that give what he calls communication systems their boundaries and coherence.
Salem, A
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Discrete-time synchronization of chaotic systems for secure communication [PDF]

open access: yes, 2012
This paper deals with the problem of designing an exact nonlinear reconstructor for discrete-time chaotic encrypted messages. More precisely, we investigate the problem of designing a discrete-time dead-beat observer for nonlinear systems with unknown ...
Belmouhoub, Inaâm   +7 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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