Results 41 to 50 of about 62,523 (216)
SAGE Open Medical Case Reports, 2014 Obsessive-compulsive disorder is a chronic and disabling condition that often proves to be treatment resistant. Of the patients suffering from obsessive-compulsive disorder, 10%–27% may attempt suicide at least once in their life. We report the case of a
Maria S Signorelli +5 more
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The Effectiveness of Acceptance and Commitment Therapy(ACT) enriched with Compassion Focus Therapy(CFT) for high school males obsession with obsessive-compulsive disorder [PDF]
مطالعات روانشناختی, 2018 The purpose of this study was to determine the effectiveness of Acceptance and Commitment Therapy (ACT) enriched with compassion for high school students’ obsession with obsessive-compulsive disorder in Isfahan. The research method was quasi-experimental
Saeed Zahiri +2 more
doaj +1 more source
CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting
Clinical Pharmacology &Therapeutics, EarlyView.CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park +2 more
wiley +1 more source
The Role of Stress in the Pathogenesis and Maintenance of Obsessive-Compulsive Disorder
Chronic Stress, 2018 Individuals with obsessive-compulsive disorder often identify psychosocial stress as a factor that exacerbates their symptoms, and many trace the onset of symptoms to a stressful period of life or a discrete traumatic incident.
Thomas G. Adams +5 more
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Clinical Pharmacology &Therapeutics, EarlyView.Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples +10 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota +8 more
wiley +1 more source
Fiyz̤, 2020 Background: This study aimed to compare the effectiveness of treatment based on Moritz metacognitive approach and Wells metacognition approach on obsessive-compulsive symptoms and cognitive flexibility of obsessive-compulsive homeowners.
Azizi R +3 more
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International Journal of Eating Disorders, EarlyView.ABSTRACT Defining recovery in eating disorders remains a major challenge due to the absence of standardized, empirically validated criteria. Bardone‐Cone et al. (2025) address this gap by testing multidimensional, transdiagnostic recovery criteria spanning physical, behavioral, and cognitive domains.
Charlotte Bovenberg +3 more
wiley +1 more source
South African Journal of Psychiatry, 2013 This guideline focuses on the pharmacotherapy of obsessive compulsive disorder(OCD). OCD is characterised by obsessions andcompulsions. A number of other disorders are also characterised byrepetitive thoughts and rituals and may also respond to ...
D J Stein
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International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anxiety and avoidance behaviors are increasingly recognized as key drivers of anorexia nervosa. Exposure therapy, rooted in the inhibitory learning model, targets these drivers by violating threat expectancies. This translational study investigated the dynamics of fear and threat expectancies within and between 417 individualized ...
Hanna Melles +3 more
wiley +1 more source