Results 61 to 70 of about 157,470 (297)

Clinical features of and influencing factors of obsessive-compulsive personality disorder in patients with obsessive-compulsive disorder

Sichuan jingshen weisheng
BackgroundObsessive-compulsive personality disorder and obsessive-compulsive disorder （OCD） are common psychological disorders with similar clinical symptoms， but the differences between the two need further clarification.ObjectiveTo explore the clinical
Jiang Wenjing, Wang Xuhui, Xu Zhihan, Zhang Xuedi, Wang Zhongqi, Zhou Ping, Liu Na   +6 more
doaj   +1 more source

The mediating roles of disgust sensitivity and danger expectancy in relation to hand washing behaviour [PDF]

, 2010
Copyright © 2010 British Association for Behavioural and Cognitive PsychotherapiesBackground: Recent interest in the role of vulnerability factors in obsessional washing has suggested that disgust sensitivity, danger expectancy and health anxiety may be ...
Beck, Julie Barnett, Kate Nottingham, Katy Friend, Nunnally, Rachman, Susan J. Thorpe   +6 more
core   +1 more source

Prevalence of Obsessive-Compulsive Spectrum Disorders in Obsessive-Compulsive Disorder

Indian Journal of Psychological Medicine, 2018
There is growing awareness of the heterogeneity of obsessive-compulsive disorder (OCD) and of the multiple systems involved in its pathogenesis. Identification of obsessive-compulsive spectrum disorders (OCSDs) may have important implications in the management and prognosis of OCD, but there is a paucity of research in the domain of identification of ...
Mohammad Aleem Siddiqui, Daya Ram, Sanjay Kumar Munda, Shazia Veqar Siddiqui, Sujit Sarkhel   +4 more
openaire   +4 more sources

The interplay between molecular architecture, pharmacology, and suspected adverse drug reactions associated with nonsteroidal androgen antagonists in the United Kingdom

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon, Albert A. Antolin, Alan M. Jones   +2 more
wiley   +1 more source

The Effectiveness of Acceptance and Commitment Therapy(ACT) enriched with Compassion Focus Therapy(CFT) for high school males obsession with obsessive-compulsive disorder [PDF]

مطالعات روانشناختی, 2018
The purpose of this study was to determine the effectiveness of Acceptance and Commitment Therapy (ACT) enriched with compassion for high school students’ obsession with obsessive-compulsive disorder in Isfahan. The research method was quasi-experimental
Saeed Zahiri, Akram Dehghani, Razieh Izady   +2 more
doaj   +1 more source

Whole-genome association analysis of treatment response in obsessive-compulsive disorder. [PDF]

, 2016
Up to 30% of patients with obsessive-compulsive disorder (OCD) exhibit an inadequate response to serotonin reuptake inhibitors (SRIs). To date, genetic predictors of OCD treatment response have not been systematically investigated using genome-wide ...
Askland, KD, Bienvenu, OJ, Cullen, BA, Fyer, AJ, Geller, D, Goes, FS, Grados, MA, Greenberg, BD, Knowles, JA, Lange, C, Liang, K-Y, Maher, B, Mattheisen, M, McCracken, JT, McLaughlin, NC, Murphy, DL, Nestadt, G, Nurmi, EL, Pauls, D, Piacentini, J, Pulver, AE, Qin, H, Rasmussen, SA, Riddle, MA, Samuels, JF, Shugart, YY, Stewart, SE, Valle, D, Wang, Y, Zhu, Y   +29 more
core   +2 more sources

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors

SAGE Open Medical Case Reports, 2014
Obsessive-compulsive disorder is a chronic and disabling condition that often proves to be treatment resistant. Of the patients suffering from obsessive-compulsive disorder, 10%–27% may attempt suicide at least once in their life. We report the case of a
Maria S Signorelli, Carmen Concerto, Eliana Battaglia, Maria C Costanzo, Fortunato Battaglia, Eugenio Aguglia   +5 more
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

The Role of Stress in the Pathogenesis and Maintenance of Obsessive-Compulsive Disorder

Chronic Stress, 2018
Individuals with obsessive-compulsive disorder often identify psychosocial stress as a factor that exacerbates their symptoms, and many trace the onset of symptoms to a stressful period of life or a discrete traumatic incident.
Thomas G. Adams, Benjamin Kelmendi, C. Alex Brake, Patricia Gruner, Christal L. Badour, Christopher Pittenger   +5 more
doaj   +1 more source