Results 121 to 130 of about 78,183 (259)

The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares, Jacy Bezerra Parmera, Pedro Augusto Sampaio Rocha‐Filho   +2 more
wiley   +1 more source

Living with the Unknown: Intolerance of Uncertainty in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is marked by pervasive uncertainty due to fluctuating motor and non‐motor symptoms, variable treatment response, and an unpredictable clinical course. Intolerance of uncertainty (IU), a tendency to perceive ambiguity as threatening and respond with worry, avoidance, or decisional paralysis, may be ...
Bradley McDaniels, Gregory M. Pontone, Kuhan Pushparatnam, Indu Subramanian   +3 more
wiley   +1 more source

Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements

Movement Disorders, EarlyView.
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano, Cécile Galléa, Asya Ekmen, Cécile Delorme, Eavan M. McGovern, Quentin Salardaine, Lina Daghsen, Manon Gomes, Vanessa Brochard, Eoin Mulroy, Kailash P. Bhatia, Carlo Fusco, Miryam Carecchio, Norbert Brüggemann, Alexander Münchau, Victoria Gonzalez, Diane Doummar, Christine Tranchant, Mathieu Anheim, Philippe Damier, Florence Riant, Mohamed Doulazmi, Agathe Roubertie, Caroline Dubacq, Oriane Trouillard, Romain Valabregue, Mélanie Didier, Benoit Beranger, Pierre Pouget, Marie Vidailhet, Sabine Meunier, Aurélie Méneret, Yulia Worbe, Emmanuel Roze   +33 more
wiley   +1 more source

Key aspects to consider in the design of prevention efforts for obsessive-compulsive disorder. [PDF]

World Psychiatry
Mataix-Cols D, Aspvall K, Leckman JF.
europepmc   +1 more source

Management of obsessive-compulsive disorder with fluvoxamine extended release

, 2009
Lídia Ordacgi1, Mauro V Mendlowicz2, Leonardo F Fontenelle11Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal do Rio de Janeiro (IPUB/UFRJ), Rio de Janeiro, Brazil; 2Department of Psychiatry and Mental ...
Lídia Ordacgi, Leonardo F Fontenelle, Mauro V Mendlowicz   +2 more
core  

Clinical Predictors of Tic‐Related Impairment in Children and Adults with Tourette Syndrome

Movement Disorders, EarlyView.
Abstract Background Tic‐related impairment drives treatment decisions for Tourette syndrome and related tic disorders. The clinical features most strongly associated with impairment remain unclear. Objective The aim of this analysis is to identify clinical predictors of tic‐related impairment in children and adults with tic disorders in a prospective ...
Wm. Jeptha Davenport, Davide Martino, Christos Ganos, Christelle Nilles, Tamara Pringsheim   +4 more
wiley   +1 more source

Mental Health and Corresponding Interventions for Persons With Physical Disabilities: A Scoping Review

Medicine Advances, EarlyView.
This scoping review of 33 studies maps the landscape of mental health in persons with physical disabilities. It finds a high prevalence of depression, anxiety, posttraumatic stress disorder, and other psychological problems, but highlights significant heterogeneity across studies in sample size, measurement, and representativeness.
Hui Li, Mengqian Li, Hongguang Chen, Xueting Bai, Qi Qiu, Nanqi Fan, Xin Wu, Xing Wang   +7 more
wiley   +1 more source

Rehabilitation needs of long COVID patients in British Columbia

PM&R, EarlyView.
Abstract Introduction COVID‐19 can result in persistent symptoms and functional impairment that significantly impact daily functioning, highlighting the need for targeted rehabilitation. However, there is a lack of data on what proportion of long COVID patients need rehabilitation and which types are required.
Débora M. Petry Moecke, Evan H. Kwong, Sonya Cressman, Jennifer Yao, Chiara Singh, Carolyn Taylor, Pat G. Camp   +6 more
wiley   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source