Results 71 to 80 of about 78,183 (259)

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Treatment and 12-month outcome of children and adolescents with obsessive–compulsive disorder : A naturalistic study

, 2015
Pediatric obsessive-compulsive disorder (OCD) is a disorder associated with distress and impairment in many domains. Moreover, there is a high risk of relapse and developing a chronic illness.
Ivarsson, Tord,, Storm Mowatt Haugland, Bente,, Holmgren Melin, Karin,, Skärsäter, Ingela,   +3 more
core   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

‘Not just right experience’ (NJRE) in obsessive-compulsive disorder: Is NJRE a manifestation of autistic traits?

, 2014
Aims: Harm avoidance (HA) and ‘not just right experience’ (NJRE) have been proposed to be two core motivational processes underlying obsessive-compulsive disorder (OCD).
Hellriegel, J
core  

Response inhibition to emotional faces in childhood obsessive-compulsive disorder

, 2014
Background and objectives Evidence regarding the role of response inhibition in obsessive-compulsive disorder (OCD) is inconsistent. Most prior research has examined response inhibition to emotionally neutral stimuli or task demands.
Waters, Allison M, Lara J. Farrell, Farrell, Lara J, Allison M. Waters   +3 more
core   +1 more source

Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive‐Compulsive Symptomatology

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Although obsessive‐compulsive disorder (OCD) commonly co‐occurs with anorexia nervosa and bulimia nervosa, less is known about its relationship with avoidant/restrictive food intake disorder (ARFID) dimensions. Whether associations between ARFID dimensions and OCD differ by sex is also unclear.
Mariana Valdez Aguilar, Gabriela K. Giulumian, Isabel Rodriguez, Jessica H. Baker, Preina P. Surti, Lisa Dinkler, Jerry Guintivano, Jessica S. Johnson, Casey M. MacDermod, Shelby N. Ortiz, Emily M. Pisetsky, Jennifer P. White, Nadia Micali, Cynthia M. Bulik, Laura M. Thornton, Ya‐Ke Wu   +15 more
wiley   +1 more source

Obsessive-compulsive disorder in a patient with SCA type 1

, 2019
For many years, the cerebellum was thought to be only responsible for balance, movement, planning and execution. Nowadays, it is well accepted that most cerebellar connections are involved in non-motor functions. Herein, we provide a case report in which
Lourenço, Charles Marques, Ataliba, Gabriela Santana, Charles Marques Lourenço, Fernando Machado Vilhena Dias, Mesquita, Leonardo Mendes, Dias, Fernando Machado Vilhena, Gabriela Santana Ataliba, Leonardo Mendes Mesquita   +7 more
core   +1 more source

Impact of COVID‐19 Lockdown on Psychopathology at the Onset of Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Previous research has shown that the COVID‐19 pandemic worsened eating‐disorder (ED) symptoms, but most studies have focused on inpatients and compared only two periods: pre‐COVID and the period following the pandemic's onset. Outpatient populations, particularly those with binge eating disorder (BED) and other specified feeding or ...
Elvira Anna Carbone, Cristiano Dani, Matteo Geraci, Alessia Romeo, Ana Jiménez‐Peinado, Marianna Rania, Enrico Lodovici, Valentina Zofia Cordasco, Emanuele Cassioli, Eleonora Rossi, Livio Tarchi, Valdo Ricca, Giovanni Castellini, Cristina Segura‐Garcia   +13 more
wiley   +1 more source

Obsessive compulsive disorder and obsessive compulsive personality disorder and the criminal law

Psychiatry, Psychology and Law, 2020
Obsessive compulsive disorder (OCD) is a mental illness that has penetrated public consciousness. However, the extent to which OCD and obsessive compulsive personality disorder (OCPD) can constitute debilitating conditions that adversely affect most aspects of a person's functioning and quality of life are not so well known, including as to how they ...
openaire   +3 more sources

Examining Comorbid Psychopathology Symptoms as Predictors of Family Based Treatment for Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa in a Real‐World Setting

European Eating Disorders Review, EarlyView.
ABSTRACT Background For adolescents with Anorexia Nervosa (AN) or Atypical Anorexia Nervosa (AAN), Family Based Treatment (FBT) is an effective treatment. However, outcomes remain suboptimal, making investigations into predictors of outcome important. Most prior research into FBT has focussed on parental and family factors as predictors.
Daniel Wilson, Hilary Grimmer, Renata A. Mendes, Jenna Irwin, Julie Atherton, Richard Litster, Jacinda White, Natalie J. Loxton   +7 more
wiley   +1 more source