Results 51 to 60 of about 916,759 (296)
Web 2.0 Technologies in Business: Why not? [PDF]
Interdisciplinary Description of Complex Systems, 2019 The objective of the study was to explore the barriers or the reasons behind the insufficient use of Web 2.0 technology in companies. The empirical research was conducted among managers in companies in Bosnia and Herzegovina during 2015.
Mirela Mabić +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Adverse Events following Cancer Immunotherapy: Obstacles and Opportunities
Trends in immunology, 2019 Oncology has recently undergone a revolutionary change with widespread adoption of immunotherapy for many cancers. Immunotherapy using monoclonal antibodies against “checkpoint” molecules, including PD-1, PD-L1, and CTLA-4, is highly effective in a ...
Kristen E. Pauken +4 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles
Nature Reviews Cardiology, 2018 A large body of evidence indicates that mitochondrial dysfunction has a major role in the pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary efforts have been focused on the development of agents that specifically ...
M. Bonora +5 more
semanticscholar +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
DETERMINANTS OF THE STRATEGIES ADOPTED BY COMPANIES EXPORTING DATES IN ALGERIA: STATE OF BISKRA AS A CASE STUDY [PDF]
Russian Journal of Agricultural and Socio-Economic Sciences, 2022 The development of the agricultural sector in Algeria is a major challenge at the economic, public and social level. A considerable potential of agricultural products that can be exploited to achieve non-hydrocarbon exports.
Abdelmalek H., Bouzid A., Boudedja K.
doaj
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source