Results 91 to 100 of about 156,286 (339)

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Association of urinary misfolded protein quantification with preeclampsia and adverse pregnancy outcomes: a retrospective case study

Journal of Perinatal Medicine
This study aimed to explore the relationship between the detection of misfolded proteins in urine and preeclampsia (PE) as well as adverse pregnancy outcomes.
Zhao Shuang, Zhang Mingju, Yang Jingyuan, Du Zhuoran, Wang Guohui, Shan Shufan   +5 more
doaj   +1 more source

Preterm birth rates and risk factors among women with cervical incompetence undergoing prophylactic cerclage: a systematic review and meta-analysis

Journal of Obstetrics and Gynaecology
Background Preterm birth is the leading cause of neonatal mortality and long-term health complications. Cervical cerclage (CC) represents a critical intervention for extending pregnancy duration and enhancing neonatal survival in patients diagnosed with ...
Jing Wang, Hui-Juan Rong, Xiao-Mei Wang, Guo-Yuan Shi, Wen-Hui Song   +4 more
doaj   +1 more source

Intensity of perinatal care for extremely preterm babies and outcomes at a higher gestational age: evidence from the EPIPAGE-2 cohort study

BMC Pediatrics, 2020
Background Perinatal decision-making affects outcomes for extremely preterm babies (22–26 weeks’ gestational age (GA)): more active units have improved survival without increased morbidity. We hypothesised such units may gain skills and expertise meaning
Andrei Scott Morgan, Babak Khoshnood, Caroline Diguisto, Laurence Foix L’Helias, Laetitia Marchand-Martin, Monique Kaminski, Jennifer Zeitlin, Gérard Bréart, François Goffinet, Pierre-Yves Ancel   +9 more
doaj   +1 more source

A ruptured vulvar labial artery pseudoaneurysm causes a secondary postpartum hemorrhage: A case report. [PDF]

, 2020
Background:Postpartum hemorrhage is the most common cause of maternal morbidity in the United States. However, secondary postpartum hemorrhage is rare and includes pseudoaneurysms, which represent only 3.3% of all cases of secondary postpartum hemorrhage.
Lane, Felicia, Leaf, Marie-Claire, Schmidt, Luke, Serna-Gallegos, Tasha   +3 more
core  

Obstetrics for Nurses [PDF]

The American Journal of Nursing, 1906
3d ed., thoroughly rev. and enl. ; 512 p.
openaire   +1 more source

Hypoxia‐Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis

Advanced Science, EarlyView.
Hypoxia triggers lactylation of PRMT1 at K134/K145, enhancing its methyltransferase activity to asymmetrically dimethylate vimentin R64. This post‐translational cascade promotes vimentin filament assembly, cytoskeletal remodeling, and tumor metastasis, with PRMT1 inhibition (MS023) reducing metastatic colonization.
Jia Zhou, Shuying Qiu, Xia Yang, Yan Wu, Xinxia Yao, Hangqi Hu, Jingfeng Luo, Chandra Sugiarto Wijaya, Lingfeng Ma, Xiaojun Long, Lingna Xu, Jinquan Liu, Chaoqun Wang, Yibin Pan, Xiaona Chen, Hongchuan Jin, Xian Wang   +16 more
wiley   +1 more source

Changes in use and outcomes after fibrinogen concentrate insurance coverage for critical obstetrical hemorrhage: a nationwide questionnaire survey in Japan

Scientific Reports
Fibrinogen concentrate (FC) for acquired hypofibrinogenemia associated with critical obstetrical hemorrhage (COH) was covered by public medical insurance in September 2021 in Japan.
Masafumi Nii, Tomoaki Oda, Mamoru Morikawa, Yasushi Nakabayashi, Tomoko Adachi, Takao Kobayashi, Atsuo Itakura   +6 more
doaj   +1 more source

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Advanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara   +17 more
wiley   +1 more source

Hydrogen sulfide in placental development and pregnancy disorders: mechanisms, therapeutic potential, and translational challenges

Reproductive Biology and Endocrinology
The placenta plays a crucial role in maintaining pregnancy stability, regulating fetal growth, and facilitating maternal–fetal exchange. Its proper development relies on placental vasculogenesis and angiogenesis, along with adaptive remodeling of the ...
Lijia Du, Rui Zheng, Weina Ren, Yingru Liu, Xiaoxiong Zhu, Shiyang Chang, Zhifen Yang   +6 more
doaj   +1 more source