Results 91 to 100 of about 73,730 (304)

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Obstetrical Instrument Collection

A number of traditional patient care and obstetrical tools are enclosed in a 1960s era Doctor\u27s Office Cabinet. At the top of the cabinet are nursing textbooks, a white metal bedpan, glass urinal, and a maroon porcelain bedpan.
Museum of Medical History,
core   +1 more source

Establishment and application of a rapid molecular diagnostic platform for the isothermal visual amplification of group B Streptococcus based on recombinase polymerase

Frontiers in Cellular and Infection Microbiology
With growing concerns about Group B streptococcal (GBS) infections and their adverse effects on perinatal pregnancies, including infection, premature delivery, neonatal septicemia, and meningitis, it is urgent to promote GBS screening at all pregnancy ...
Meilin Liu, Huan Wang, Chu Chu, Fanli Min, Lizhou Sun, Teng Zhang, Qian Meng   +6 more
doaj   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Psychological status of pregnant women during the omicron pandemic outbreak in China

BMC Women's Health
Background Pregnant women faced great challenges and psychological and physiological changes of varying degrees during the omicron epidemic outbreak. It is important to recognize the potential impact of these challenges on the mental health of pregnant ...
Shuting Bao, Bangwu Chen, Shuqi Zhu, Ying Hu, Chee Shin Lee, Mengkai Du, Menglin Zhou, Danfeng Fan, Biao Xie, Huimin Gu, Zhaoxia Liang   +10 more
doaj   +1 more source

Development of an efficient strategy to improve HPV immunization coverage in Japan

BMC Public Health, 2016
Background In Japan, new HPV immunizations have dropped dramatically after repeated adverse media reports and a June 2013 temporary suspension of the government’s recommendation for the vaccine.
Asami Yagi, Yutaka Ueda, Tomomi Egawa-Takata, Yusuke Tanaka, Akiko Morimoto, Yoshito Terai, Masahide Ohmichi, Tomoyuki Ichimura, Toshiyuki Sumi, Hiromi Murata, Hidetaka Okada, Hidekatsu Nakai, Masaki Mandai, Kiyoshi Yoshino, Tadashi Kimura, Junko Saito, Risa Kudoh, Masayuki Sekine, Takayuki Enomoto, Kei Hirai, Yorihiko Horikoshi, Tetsu Takagi, Kentaro Shimura   +22 more
doaj   +1 more source

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Metabolomics of saliva, serum, and urine for pathogenesis, diagnosis, and prognosis in gestational diabetes mellitus

Nature Communications
Gestational diabetes mellitus (GDM) is a common metabolic disorder in pregnancy, but the underlying mechanism has not been fully clarified. Using metabolomic profiling of second-trimester saliva, serum, and urine, we identify 54 metabolites altered in ...
Qi Wu, Yihui Wu, Shuqi Zhu, Yibo Tang, Lixia Zhang, Jiayue Tang, Qi Chen, Luyao Hu, Pingya Zhu, Xuliang Fu, Jianghai Chang, Sheng Cao, Danqing Chen, Zhaoxia Liang   +13 more
doaj   +1 more source

Weight-gain-for-gestational-age z-score in twin pregnancies in China and its association with preterm birth: a retrospective cohort study

Journal of Obstetrics and Gynaecology
Background To evaluate the association between the weight-gain-for-gestational-age z-score and preterm birth (PTB) in a large Chinese twin pregnancy cohort.Methods A hospital-based retrospective study included 2832 twin pregnancies between January 1 ...
Ying Hu, Shuqi Zhu, Jia Liu, Die Hong, Hong Wen, Lu Chen, Xixi Chen, Yuqing Zou, Jingjing Liu, Danqing Chen, Lu Qi, Zhaoxia Liang   +11 more
doaj   +1 more source

Changes in Maternal Glucose Metabolism after the Administration of Dexamethasone for Fetal Lung Development

International Journal of Endocrinology, 2012
Aims. Antenatal dexamethasone administration for fetal lung development may impair maternal glucose tolerance. In this study, we investigated whether glucose and insulin levels differed among singleton and twin pregnancies and pregnancies with impaired ...
Xu Jian Yun, Liang Zhaoxia, Chai Yun, Fang Qin, Chen Yuanyuan, Chen Danqing   +5 more
doaj   +1 more source