Results 21 to 30 of about 74,948 (256)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Correlation Between Blood Glucose Variability Indices Using Continuous Glucose Monitoring in Gestational Diabetes Patients and Abnormal Glucose Levels 42 Days Postpartum

Journal of Diabetes Research
Trial Registration: Chinese Clinical Trial Registry number ...
Rui Wang, Yuping Zhang, Huiqian Zeng, Jinyan Xiao, Mingming Qi, Lei Bao, Ruifen Jiao, Jing Liu, Yichun Li, Shuli He, Yunlong Li, Rui Li, Fan Ping, Yanping Liu   +13 more
doaj   +1 more source

Comparison of population characteristics, obstetrical conditions and obstetrical outcomes between women with higher and lower satisfaction scores regarding the optimized position.

, 2021
Comparison of population characteristics, obstetrical conditions and obstetrical outcomes between women with higher and lower satisfaction scores regarding the optimized position.
David Desseauve (8798543), Lisa Bouille (11419569), Joanna Sichitiu (11370465), Julien Favre (11419572)   +3 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Comparative Evaluation of Two Doses of Intrathecal Dexmedetomidine (3 µg vs 5 µg) as an Adjuvant to Hyperbaric Ropivacaine in Caesarean Section: A Randomised Double-blind Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Spinal anaesthesia is commonly used for caesarean sections because of its rapid onset, reliable sensory and motor blockade, and excellent analgesia. Ropivacaine is preferred for its improved safety profile and reduced motor block.
Himani Taiwade, Dipakkumar Ruparel, Krunal Borkar, Shweta Sedani   +3 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Network meta-analysis: comparative efficacy of diverse aspirin dosages and heparin in mitigating placenta-mediated pregnancy complications

BMC Pregnancy and Childbirth
Objective This study aimed to assess the comparative efficacy of different low-dose aspirin (ASA) dosages, either alone or in combination with heparin, in preventing placenta-mediated pregnancy complications (PMPC) among high-risk pregnant women using a ...
Zhihui Xiong, Shenglin Jiang, Zhouhui Yuan, Lijie Li, Yunmeng Chen   +4 more
doaj   +1 more source

Unravelling Multilayered RNA Modification Networks in Female Reproduction and Obstetric/Gynaecologic Disorders

Biomolecules
Background/Objective: RNA modifications, including N6-methyladenosine (m6A), 5-methylcytosine (m5C), 7-methylguanosine (m7G), N1-methyladenosine (m1A), pseudouridine (Ψ), N4-acetylcytidine (ac4C), 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) and ...
Yujie Kuai, Yanjun Yi, Xinyu Li, Zhuangping Wang, Yan Zheng, Yuxuan Li, Yulin Li   +6 more
doaj   +1 more source

Effects of Intradermal Sterile Water Injections in Women with Low Back Pain in Labor: A Randomized, Controlled, Clinical Trial

Balkan Medical Journal, 2018
Background: In addition to the pain caused byuterine contractions during labour, continuous and severe back pain is observed in 33% of women. Several pharmacological and nonpharmacological methods are available for managing this pain.
Refika Genç Koyucu, Nurdan Demirci, Ayşe Ender Yumru, Süleyman Salman, Yavuz Tahsin Ayanoğlu, Yıldız Tosun, Cihangir Tayfur   +6 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source