Results 41 to 50 of about 74,948 (256)

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Current Practice in Obstetric Anesthesia and Analgesia in Public Hospitals of Greece: A 2016 National Survey

Balkan Medical Journal, 2018
Aims:This descriptive survey was to evaluate the use of regional anesthesia in obstetrics in Greek public hospitals.Methods:The survey was conducted between March and August 2016.
Chryssoula Staikou, Alexandros Μakris, Kassiani Theodoraki, Athanasia Τsaroucha, Amalia Douma, Eleni Μoka, Eleni Αrnaoutoglou, Tilemahos Paraskevopoulos, Ioanna Siafaka, Efi Stavropoulou, Eriphili Αrgyra   +10 more
doaj   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Gynecological Obstetrical Society 1939

, 1939
Gynecological Obstetrical Society 1939, 1938-39, group photograph. Bluejay 1939-40, p.
Creighton University
core   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Optimal programmed intermittent epidural bolus volume for dural puncture epidural labor analgesia in patients with gestational hypertension: a biased-coin up-and-down sequential allocation trial

Frontiers in Medicine
BackgroundThis study aimed to evaluate the effective programmed intermittent epidural bolus (PIEB) volume and the efficacy of dural puncture epidural (DPE) for labor analgesia in patients with gestational hypertension (GH).MethodsFifty primiparous women ...
Binghui Zhang, Hongyang Zhang, Yuan Wu, Kai Zhao, Yancen Meng   +4 more
doaj   +1 more source

Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery [PDF]

Einstein (São Paulo), 2009
Objective: To identify the types of pharmacological and non-pharmacological treatments used during hospitalization, in the relief of perineal pain after vaginal deliveries.
Joyce Hasegawa, Lucila Coca Leventhal
doaj  

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Pain Ratings and Pharmacological Pain Management in Australian Breastfeeding Women After a Caesarean Section Birth

Proceedings
Caesarean section (CS) birth is associated with pain and reduced mobility that impacts a woman’s ability to breastfeed and care for her newborn infant [...]
Jasmine E. Hunt, Philip Vlaskovsky, Ching T. Lai, Sarah G. Abelha, Jacki L. McEachran, Stuart A. Prosser, Donna T. Geddes, Sharon L. Perrella   +7 more
doaj   +1 more source

The small dense LDL particle/large buoyant LDL particle ratio is associated with glucose metabolic status in pregnancy

Lipids in Health and Disease, 2017
Background The lipoprotein subfraction particle profile can be used to improve clinical assessments of cardiovascular disease risk and contribute to early detection of atherogenic dyslipidemia.
Yanmin Chen, Mengkai Du, Jianyun Xu, Danqing Chen   +3 more
doaj   +1 more source