Results 71 to 80 of about 159,829 (340)

Changes in Maternal Glucose Metabolism after the Administration of Dexamethasone for Fetal Lung Development

International Journal of Endocrinology, 2012
Aims. Antenatal dexamethasone administration for fetal lung development may impair maternal glucose tolerance. In this study, we investigated whether glucose and insulin levels differed among singleton and twin pregnancies and pregnancies with impaired ...
Xu Jian Yun, Liang Zhaoxia, Chai Yun, Fang Qin, Chen Yuanyuan, Chen Danqing   +5 more
doaj   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Establishment and application of a rapid molecular diagnostic platform for the isothermal visual amplification of group B Streptococcus based on recombinase polymerase

Frontiers in Cellular and Infection Microbiology
With growing concerns about Group B streptococcal (GBS) infections and their adverse effects on perinatal pregnancies, including infection, premature delivery, neonatal septicemia, and meningitis, it is urgent to promote GBS screening at all pregnancy ...
Meilin Liu, Huan Wang, Chu Chu, Fanli Min, Lizhou Sun, Teng Zhang, Qian Meng   +6 more
doaj   +1 more source

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

Advanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma   +12 more
wiley   +1 more source

Psychological status of pregnant women during the omicron pandemic outbreak in China

BMC Women's Health
Background Pregnant women faced great challenges and psychological and physiological changes of varying degrees during the omicron epidemic outbreak. It is important to recognize the potential impact of these challenges on the mental health of pregnant ...
Shuting Bao, Bangwu Chen, Shuqi Zhu, Ying Hu, Chee Shin Lee, Mengkai Du, Menglin Zhou, Danfeng Fan, Biao Xie, Huimin Gu, Zhaoxia Liang   +10 more
doaj   +1 more source

Exploring Biomedical, Temporal, and Embodied Perspectives on the Timing of Birth in Central Nepal [PDF]

, 2018
As an ANHS Senior Fellow, I began to explore the standardization of time in obstetrics and its translation into everyday practice in Nepal by analyzing the various perspectives involved in determining a woman’s ideal time of delivery and a successful ...
Brunson, Jan, Tamrakar, Suman Raj
core   +3 more sources

Grand multiparity and obstetric outcomes in a contemporary cohort: the role of parity [PDF]

, 2021
Chelsea A. DeBolt, Meghana Limaye, Ashley S. Roman, Viktoriya London, Howard Minkoff, Deepika Sagaram, Peter S. Bernstein, Lorraine E. Toner, Victoria Mroz, Rachel Meislin, Aayushi Jain, Melissa Magenta, Ayisha Buckley, Jessica Overbey, Joanne Stone   +14 more
openalex   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Metabolomics of saliva, serum, and urine for pathogenesis, diagnosis, and prognosis in gestational diabetes mellitus

Nature Communications
Gestational diabetes mellitus (GDM) is a common metabolic disorder in pregnancy, but the underlying mechanism has not been fully clarified. Using metabolomic profiling of second-trimester saliva, serum, and urine, we identify 54 metabolites altered in ...
Qi Wu, Yihui Wu, Shuqi Zhu, Yibo Tang, Lixia Zhang, Jiayue Tang, Qi Chen, Luyao Hu, Pingya Zhu, Xuliang Fu, Jianghai Chang, Sheng Cao, Danqing Chen, Zhaoxia Liang   +13 more
doaj   +1 more source