Results 31 to 40 of about 479,851 (266)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Antenatal screening for TB disease: a systematic review and meta-analysis

IJTLD Open
OBJECTIVES: TB disease during pregnancy is associated with poor maternal and neonatal outcomes, and is a leading non-obstetric cause of maternal death. However, optimal detection strategies remain uncertain.
A.J. Morton, N. Meagher, G. Tonkin-Hill, J.T. Denholm, R.I. Zahroh, S.J. Dunstan   +5 more
doaj   +1 more source

Emergency Medical Services (EMS) Utilization in Zimbabwe: Retrospective Review of Harare Ambulance System Reports

Annals of Global Health, 2022
Background: Emergency medical services (EMS) are a critical but often overlooked component of essential public health care delivery in low- and middle-income countries (LMICs). Few countries in Africa have established EMS and there is scant literature to
Monalisa Muchatuta, Soman Mudariki, Loretta Matheson, Brian Rice, Midion Chidzonga, Rebecca Walker, Matthew Strehlow, Jennifer Newberry   +7 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

“I honestly didn’t know it was for women too…” acceptability and feasibility of integrating PrEP services into OB/GYN practices from the perspectives of practice staff and cisgender women in the community: a qualitative study

Frontiers in Health Services
BackgroundHIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but uptake among cisgender women in the United States (US) is suboptimal.
Christine M. Khosropour, Elise Healy, Emma M. Murphy, Arianna Rubin Means, Erykah Pasha, Jaelyn Howard, Emani Gonzalez, Tiffany D. Lloyd, Bethany Spier, Cathy J. Berry, Kandis V. Backus   +10 more
doaj   +1 more source

Hyaluronic acid in gynecology and obstetrics

Journal of Education, Health and Sport, 2022
Introduction: Hyaluronic acid (HA) is a polysaccharide classified in the group of glycosaminoglycans. Naturally it occurs in the dermis and is responsible for the elasticity of the skin.
Anna Małgorzata Łopuszyńska, Łukasz Ochyra, Mateusz Pawlicki, Halina Piecewicz-Szczęsna   +3 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

CORRELATION OF AMNIOTIC FLUID INDEX VALUES WITH MATERNAL AND PERINATAL OUTCOMES IN PRETERM PREMATURE RUPTURE OF MEMBRANES.

Student's Journal of Health Research Africa
Background: Preterm Premature Rupture of Membranes (PPROM) is a significant obstetric complication associated with adverse neonatal outcomes. This study aims to evaluate the relationship between Amniotic Fluid Index (AFI) levels and clinical outcomes ...
Vamsi Priya , Varada A Hasamnis , Munukutla Vaidehi   +2 more
doaj   +1 more source

A Laryngoscope for Obstetrical Use an Obstetrical Laryngoscope [PDF]

Anaesthesia and Intensive Care, 1977
Rapid tracheal intubation, using the standard Macintosh laryngoscope, can be hindered in obstetrical patients by the handle of the laryngoscope hitting the patient's engorged breasts and the hand of the assistant applying cricoid pressure. To overcome these difficulties a variation of the laryngoscope is described.
openaire   +2 more sources

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour   +7 more
wiley   +1 more source