Results 71 to 80 of about 112,839 (305)
The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1
Advanced Science, EarlyView.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer +10 morewiley +1 more sourceClean Cut (adaptive, multimodal surgical infection prevention programme) for low‐resource settings: a prospective quality improvement study
BJS (British Journal of Surgery), EarlyView., 2020 Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...J. A. Forrester, N. Starr, T. Negussie, D. Schaps, M. Adem, S. Alemu, D. Amenu, N. Gebeyehu, T. Habteyohannes, F. Jiru, A. Tesfaye, E. Wayessa, R. Chen, A. Trickey, S. Bitew, A. Bekele, T. G. Weiser +16 morewiley +1 more sourceCost-effectiveness of fibronectin testing in a triage in women with threatened preterm labor: alleviation of pregnancy outcome by suspending tocolysis in early labor (APOSTEL-I trial) [PDF]
, 2009 BACKGROUND: At present, women with threatened preterm labor before 32 weeks of gestation are, after transfer to a perinatal center, treated with tocolytics and corticosteroids. Many of these women are treated unnecessarily.van Pampus Maria G, Femke F Wilms, Wilms, Femke F., Scherjon Sicco A, Derks Jan B, Bolte, A.C. (Annemieke), Van der Post, JAM, Sollie, K.M. (Krystyna), Bolte, AC, Lotgering, F.K. (Fred), Lotgering, F.K., Spaanderman, M, Lotgering, FK (Fred), van Eyck, J., Bloemenkamp Kitty WM, Post, J.A. van der, Bolte, Annemiek C., van Pampus, M.G., Vis, JY, Willekes, C, Vis, J.Y., van Pampus, Marielle, Wilms, FF, Annemiek C Bolte, Eyck, J. (Jim) van, Johannes J Duvekot, Scheepers, Liesbeth C. J., Bloemenkamp, KWM, Oudijk, Martijn A., Duvekot Johannes J, Duvekot, Johannes J., Cornette, J., Bloemenkamp, K.W.M. (Kitty), van der Post, Joris A. M., Kwee, Anneke, Mol, BWJ (Ben), Opmeer, B.C., Willekes Christine, Jérôme Cornette, Krystyna M Sollie, Christine Willekes, Spaanderman Marc EA, Kwee, A., Spaanderman, M.E., Wilms, F.F., Sollie, K.M., Scheepers Hubertina CJ, Bolte, A.C., Willekes, C., Ben Willem J Mol, Opmeer Brent C, Lotgering, Fred K., van Eyck, J, van Pampus, MG, van Eyck Jim, Martina M Porath, Scheepers, H.C., Kwee, A. (Anneke), Vis Jolande Y, Scheepers, Hubertina C. J., Porath, MM, Sicco A Scherjon, Pampus, M.G. (Maria) van, Kwee Anneke, Post, J.A.M. (Joris) van der, Wilms, F.F. (Femke), Porath, M. (Martina), Pampus, M.G. van, Scherjon, Sicco A., Opmeer, BC, Eyck, J. van, Sollie, KM, Derks, J.B. (Jan), Porath, Martina M., Cornette Jérôme, Vis, J.Y. (Jolande), Mol, B.W., Bolte Annemiek C, Jim van Eyck, Marc EA Spaanderman, Scherjon, S.A., Hubertina CJ Scheepers, Jolande Y Vis, Kitty WM Bloemenkamp, Mol Ben, Bloemenkamp, Kitty W. M., van der Post, J.A., Scheepers, H.C.J., van Eyck, Jim, Opmeer, Brent C., Porath Martina M, Martijn A Oudijk, Scheepers, HC, Wilms Femke F, Derks, J.B., Spaanderman, Marc E. A., Cornette, JMJ, Fred K Lotgering, van Pampus, Maria G., Bloemenkamp, K.W., Scheepers, H.C.J. (Hubertina), Anneke Kwee, Willekes, Christine, Opmeer, B.C. (Brent), Oudijk, MA, Duvekot, J.J. (Hans), Sollie, Krystyna M., Oudijk, M.A. (Martijn), Cornette, J.M.J. (Jérôme), van der Post Joris AM, Duvekot, J.J., Scherjon, SA, Oudijk, M.A., Mol, Ben Willem J., Sollie Krystyna M, Derks, JB, Lotgering Fred K, Brent C Opmeer, Oudijk Martijn A, Scherjon, S.A. (Sico), Kwee, A, Willekes, C. (Christine), Porath, M.M., Joris AM van der Post, Maria G van Pampus, Cornette, Jerome, Duvekot, JJ, Spaanderman, M.E.A., Jan B Derks, Derks, Jan B., Mol, B.W.J. (Ben), Vis, Jolande Y. +131 morecore +1 more sourceNatural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims
Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.Shannon M. Vandriel, Li‐Ting Li, Huiyu She, Jian‐She Wang, Melissa A. Gilbert, Irena Jankowska, Piotr Czubkowski, Dorota Gliwicz‐Miedzińska, Emmanuel M. Gonzales, Emmanuel Jacquemin, Jérôme Bouligand, Nancy B. Spinner, Kathleen M. Loomes, David A. Piccoli, Lorenzo D'Antiga, Emanuele Nicastro, Étienne Sokal, Tanguy Demaret, Noelle H. Ebel, Jeffrey A. Feinstein, Rima Fawaz, Silvia Nastasio, Florence Lacaille, Dominique Debray, Henrik Arnell, Björn Fischler, Susan Siew, Michael Stormon, Saul J. Karpen, Rene Romero, Kyung Mo Kim, Woo Yim Baek, Winita Hardikar, Sahana Shankar, Amin J. Roberts, Helen M. Evans, M. Kyle Jensen, Marianne Kavan, Shikha S. Sundaram, Alexander Chaidez, Palaniswamy Karthikeyan, Maria Camila Sanchez, Maria Lorena Cavalieri, Henkjan J. Verkade, Way Seah Lee, James E. Squires, Christina Hajinicolaou, Chatmanee Lertudomphonwanit, Ryan T. Fischer, Catherine Larson‐Nath, Yael Mozer‐Glassberg, Cigdem Arikan, Henry C. Lin, Jesus Quintero Bernabeu, Seema Alam, Deirdre A. Kelly, Elisa Carvalho, Cristina Targa Ferreira, Giuseppe Indolfi, Ruben E. Quiros‐Tejeira, Pinar Bulut, Pier Luigi Calvo, Zerrin Önal, Pamela L. Valentino, Dev M. Desai, John Eshun, Maria Rogalidou, Antal Dezsőfi, Sabina Wiecek, Gabriella Nebbia, Raquel Borges Pinto, Victorien M. Wolters, María Legarda Tamara, Andréanne N. Zizzo, Jennifer Garcia, Kathleen Schwarz, Marisa Beretta, Thomas Damgaard Sandahl, Carolina Jimenez‐Rivera, Nanda Kerkar, Jernej Brecelj, Quais Mujawar, Nathalie Rock, Cristina Molera Busoms, Wikrom Karnsakul, Eberhard Lurz, Ermelinda Santos‐Silva, Niviann Blondet, Luis Bujanda, Uzma Shah, Richard J. Thompson, Bettina E. Hansen, Binita M. Kamath, The Global ALagille Alliance (GALA) Study Group +93 morewiley +1 more sourceANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer
Advanced Science, EarlyView.A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang +13 morewiley +1 more source