Results 81 to 90 of about 198,998 (340)

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

Arthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J. T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Professor of the Imperial Medical-Surgical Academy V.M. Florinsky – Scientist, Teacher and Statesman

Развитие образования, 2019
The main periods of life, scientific and state activity of Vasilij Markovich Florinsky. The purpose of the article is to consider stages of V.M.
Alexander A. Dvirskii, Anatoly E. Dvirsky, Igor I. Ivanov   +2 more
doaj   +1 more source

Recommendations for Thrombopropylaxis in Obstetrics and GynaecologyA SASOG Guideline

South African Journal of Obstetrics and Gynaecology, 2018
BackgroundVenous thrombo-embolism (VTE) is associated with considerable morbidity, mortality in the absence of thromboprophylaxis.MethodThe Southern African Society of Thrombosis and Haemostasis reviewed the available literature and comprehensive ...
Elise Schapkaitz
doaj   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

A Rare Case of Reversible Encephalopathy Syndrome Accompanying Late Postpartum Eclampsia or Hypertensive Encephalopathy-A Clinical Dilemma [PDF]

, 2012
Posterior Reversible Encephalopathy Syndrome (PRES) refers to a clinic-radiologic diagnosis. Clinically it is characterized by non specific symptoms such as headache, confusion, visual disturbances and seizures.
Appaiah, N, Isaac, P, Rashmi, N, Shakuntala, PN, Thomas, M   +4 more
core  

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Evaluation of the Assessment Plan for Undergraduate Clerkship in Obstetrics and Gynecology, King Abdulaziz University

Journal of Medical Education and Curricular Development, 2014
Background The standards set by accreditation bodies for student assessment during higher education, such as those of the National Commission for Academic Accreditation & Assessment (NCAAA), are necessary in formulating educational programs.
Ahmad M.S. Almrstani, Abdullah Alnoman, Hassan Abduljabbar, Hesham Sait, Mohammed Bazarah, Basem Eldeek   +5 more
doaj   +1 more source

Effect of folic acid supplementation in pregnancy on preeclampsia: The folic acid clinical trial study [PDF]

, 2013
Copyright © 2013 Shi Wu Wen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited ...
Champagne, J, Coyle, D, Fergusson, D, Fraser, W, Rennicks White, R, Smith, G, Walker, MC, Wen, SW   +7 more
core   +4 more sources

Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. [PDF]

, 2020
OBJECTIVE: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered
Arulkumaran, S, Balakumar, S, Muhunthan, K, Navaratnaraja, TS, Premakrishna, S   +4 more
core   +1 more source