Results 81 to 90 of about 175,708 (350)

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu   +13 more
wiley   +1 more source

Maternal Care [PDF]

open access: yes, 2001
This is the edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, London, on 6 June 2000. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2001.©The Trustee of the Wellcome ...
Christie, DA, Tansey, EM
core  

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

open access: yesAdvanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama   +17 more
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

FREQUENCY OF PRE-GESTATIONAL DIABETES MELLITUS AMONG PREGNANT WOMEN WITH MISCARRIAGE

open access: yesGomal Journal of Medical Sciences, 2019
Background: In developing countries, miscarriage is one of the common and increasing problems of pregnancy. The objectives of this study were to determine the frequency of pre-gestational diabetes mellitus among pregnant women with miscarriage in our ...
Maria Ghafoor   +5 more
doaj   +1 more source

Synergistic Anti‐Cancer Therapy Through Ultrasound‐Induced Piezocatalytic Therapy and Tumor Treatment Fields

open access: yesAdvanced Science, EarlyView.
A novel, wearable anti‐cancer platform synergistically combines tumor treating fields (TTFs) and piezocatalytic therapy (PCT) via ultrasound‐activated, lead‐free piezocomposites. This strategy efficiently suppresses tumor growth, modulates the immune microenvironment, and demonstrates strong therapeutic synergy in both mouse model of subcutaneous tumor
Jing Jin   +9 more
wiley   +1 more source

Virtual consultation (VC) in fertility and obstetrics and gynaecology services: An analysis of patient and clinician satisfaction

open access: yesReproductive, Female and Child Health
Objective To assess patient and clinician satisfaction and identify any differences between the two with the use of video consulting (VC) in the fields of obstetrics and gynaecology (O&G) and fertility in Wales.
Arianna D'Angelo   +4 more
doaj   +1 more source

Characteristics Symptoms of Imminent Eclampsia: A case Referent Study from a Tertiary Hospital in Tanzania [PDF]

open access: yes, 2012
\ud \ud Maternal mortality in developing coun- tries is unacceptably high with eclampsia being con- sistently among the top causes. As yet, primary pre- vention of this complication is not possible since causes of pre-eclampsia are largely unknown and ...
France, John, Muganyizi, Projestine S.
core  

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