Results 171 to 180 of about 670,125 (262)

False Detection of Cheyne-Stokes Respiration on Continuous Positive Airway Pressure Resolved After Treatment of Nasal Obstruction. [PDF]

Respirol Case Rep
Castermans E, Impens D, Libert W, Bruyneel M.   +3 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Subcutaneous ureteral bypass explantation in 21 cats (2015-2023): outcomes and owner perceptions. [PDF]

J Vet Intern Med
Broughton SE, Frykfors von Hekkel A, Rossanese M, Rutherford L, Geddes RF, Lawson JS.   +5 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Confronting Climate Obstruction: The Role of Civil Society and Non-State Actors

Resistance to climate obstruction is gaining momentum globally as civil society attempts to hold powerful actors accountable for intentionally delaying the transformative action required for a climate-stable future.
Fitzgerald, Louise M., Yadin, Sharon, Healy, Noel, Hess, David J., García Gibson, Francisco, Green, Fergus, Delina, Laurence L., Stephens, Jennie C., Tschoetschel, Robin, Kamuti, Tariro, Losekann, Cristiana, Michaels, David, Solomun, Sonja   +12 more
core  

An Uncommon Twist: Intussusception as a Rare Manifestation of Extramedullary Myeloma. [PDF]

Case Rep Surg
E Q, A EM, W D, P DG, D K.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Operative vs non-operative management of ventral hernia: a population based study of long-term benefits and consequences. [PDF]

Hernia
Podder SK, Baran JA, Koeneman SH, Palazzo F, Dugan NL, Keating C, Tannouri S.   +6 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Case report: abdominal cocoon syndrome following peritoneal dialysis presenting as closed-loop small bowel obstruction. [PDF]

J Surg Case Rep
Atawna IB, Dababseh BH, Ghnimat AS, AbuHamdiya LW, Dababsseh AH, Abudaia S, Maraqa M.   +6 more
europepmc   +1 more source