Results 191 to 200 of about 1,380,158 (388)

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Metabolomics Reveals Dysregulated Sphingolipid and Amino Acid Metabolism Associated with Chronic Obstructive Pulmonary Disease

, 2022
Jeeyoung Kim, Bharathi Suresh, Myoung Nam Lim, Seok‐Ho Hong, Kye-Seong Kim, Ha Eun Song, Hyo Yeong Lee, Hyun Ju Yoo, Woo Jin Kim   +8 more
openalex   +2 more sources

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Case Report: Nocardia amamiensis Infection Leading to Worsening of Chronic Obstructive Pulmonary Disease Symptoms in an Elderly Man [PDF]

, 2023
Ahalya Kanakan, Amit Kumar, Upinder Kaur, Prity Narwade, Zinnu Rain, Nidhi Yadav, Ishan Kumar, Deepak Kumar, Sankha Shubhra Chakrabarti   +8 more
openalex   +1 more source

Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report

Respirology (Carlton South. Print), 2017
C. Vogelmeier, G. Criner, F. Martinez, A. Anzueto, P. Barnes, J. Bourbeau, B. Celli, Rongchang Chen, M. Decramer, L. Fabbri, P. Frith, D. Halpin, M. V. Lopez Varela, M. Nishimura, N. Roche, R. Rodríguez-Roisín, D. Sin, Dave Singh, R. Stockley, J. Vestbo, J. Wedzicha, A. Agustí   +21 more
semanticscholar   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Long-Term Real-World Outcomes of Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy up to 108 Weeks [PDF]

Nosheen Reza, Anandkumar Dubey, Nadim Mahmud, Melissa A. Austin, Estherland Duqueney, Parth Patel, Ellen Boakye, Amy Marzolf, Nicole Hornsby, Alejandro de Feria, Thomas Carattini, P. K. Schuler, Anjali Owens   +12 more
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Self- and Goal-Directed Valsalva Maneuver vs Exercise in Eliciting Left Ventricular Outflow Tract Obstruction. [PDF]

JACC Adv
Bavishi A, Fritzlen J, Nazif K, Soutar M, Kurnides M, Speer H, Oyarce G, Richards K, Flahive C, Martinez MW.   +9 more
europepmc   +1 more source