Results 111 to 120 of about 316,363 (294)

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Low testosterone in primary infertile men is associated with a history of maternal obesity during pregnancy: Findings from a cross‐sectional study

Andrology, EarlyView.
Abstract Background Maternal obesity increases offspring obesity risk, but limited data exist on its association with reproductive hormones in infertile males. Objectives To investigate the impact of maternal obesity during pregnancy on total testosterone levels in primary infertile men.
Fausto Negri, Luca Boeri, Edoardo Pozzi, Massimiliano Raffo, Riccardo Ramadani, Gabriele Birolini, Federica Passarelli, Christian Corsini, Federico Belladelli, Alessandro Bertini, Rayan Matloob, Alessia d'Arma, Michael L. Eisenberg, Francesco Montorsi, Andrea Salonia   +14 more
wiley   +1 more source

Comparative efficacy of varicocelectomy and intrauterine insemination in varicocoele patients with mild semen abnormalities: An observational study

Andrology, EarlyView.
Abstract Background Varicocoele is a common cause of male infertility, affecting spermatogenesis through increased testicular temperature, venous stasis, and oxidative stress. Microsurgical subinguinal varicocelectomy improves semen quality, whereas intrauterine insemination is widely used for mild male factor infertility.
Yanlin Ma, Weiming Deng, Tingting Wu, Qi Li, Yuanjie Li, Wenjie Mai, Lizheng Yan, Changwei Liang, Lingxiao Zhang   +8 more
wiley   +1 more source

Techniques for microsurgical reconstruction of obstructive azoospermia

Indian Journal of Urology, 2011
About 10%-15% of infertile men present with azoospermia, and ductal obstruction is the cause in 40% of them. For about 25-30 years, microsurgical reconstruction was the only way to manage obstructive azoospermia, and several innovative techniques have been developed and implemented.
openaire   +4 more sources

RNF187 Facilitates Proliferation and Migration of Human Spermatogonial Stem Cells Through WDR77 Polyubiquitination

Cell Proliferation, EarlyView.
RNF187 mediates the polyubiquitination and subsequent degradation of WDR77, reduces H4R3me2s catalysed by the WDR77/PRMT5 complex, and derepresses the transcription of EGR1, thereby promoting the proliferation and migration of human SSCs. ABSTRACT The E3 ubiquitin ligase RNF187, also known as RING domain AP1 coactivator‐1, is a member of the RING ...
Haoyue Hu, Xiaoxue Xi, Bing Jiang, Kehan Wang, Tiantian Wu, Xia Chen, Yueshuai Guo, Tao Zhou, Xiaoyan Huang, Jun Yu, Tingting Gao, Yibo Wu, Bo Zheng   +12 more
wiley   +1 more source

New era of cystic fibrosis: full mutational analysis and personalized therapy [PDF]

, 2017
Despite its apparently simple genetics, cystic fibrosis (CF) is a rather complex genetic disease. A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator (CFTR ) gene to the clinical manifestations ...
Lucarelli, Marco
core   +1 more source

Transient Azoospermia Induced by Valganciclovir Treatment for Cytomegalovirus Infection in a Reproductive Male After Kidney Transplant: A Case Report

IJU Case Reports, Volume 8, Issue 4, Page 431-434, July 2025.
ABSTRACT Introduction Spermatogenic dysfunction is a side effect of valganciclovir, which is commonly used to treat cytomegalovirus infections. Here, we report the case of a reproductive man who underwent kidney transplantation and was diagnosed with azoospermia after valganciclovir treatment for cytomegalovirus infection.
Kosuke Mieda, Shunta Hori, Mitsuru Tomizawa, Kuniaki Inoue, Tatsuo Yoneda, Yuji Nitta, Yasushi Nakai, Makito Miyake, Nobumichi Tanaka, Kiyohide Fujimoto   +9 more
wiley   +1 more source

Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1 [PDF]

, 2013
Gonadal failure, along with early pregnancy loss and perinatal death, may be an important filter that limits the propagation of harmful mutations in the human population.
Amorim, Antonio, Aston, Kenneth I., Barros, Alberto, Carracedo, A., Carrell, D.T., Carvalho, Filipa, Conrad, D.F., Dai, Juncheng, Downie, Jonathan, Fernandes, Susana, Gonçalves, João, Guo, Xuejiang, Hu, Z., Huang, N., Hurles, M.E., Lopes, Alexandra, Matthiesen, Rune, Moskovtsev, S., Noordam, Michiel J., Ober, C., Paduch, D.A., Quintela, Ines, Ramu, Avinash, Schiffman, J.D., Schlegel, P.N., Seabra, Catarina, Shah, Jiahao, Sousa, M., Thompson, Emma E, Wilfert, Amy B.   +29 more
core   +3 more sources

Sperm recovery and ICSI outcomes in men with non-obstructive azoospermia: a systematic review and meta-analysis.

Human Reproduction Update, 2019
BACKGROUND Factor affecting sperm retrieval rate (SRR) or pregnancy rates (PR) after testicular sperm extraction (TESE) in patients with non-obstructive azoospermia (NOA) have not been systematically evaluated.
G. Corona, S. Minhas, A. Giwercman, C. Bettocchi, M. Dinkelman-Smit, G. Dohle, F. Fusco, Ates Kadioglou, S. Kliesch, Z. Kopa, C. Krausz, F. Pelliccione, A. Pizzocaro, J. Rassweiler, P. Verze, L. Vignozzi, W. Weidner, M. Maggi, N. Sofikitis   +18 more
semanticscholar   +1 more source

How exome sequencing improves the diagnostics and management of men with non‐syndromic infertility

Andrology, Volume 13, Issue 5, Page 1011-1024, July 2025.
Abstract Male infertility affects approximately 17% of all men and represents a complex disorder in which not only semen parameters such as sperm motility, morphology, and number of sperm are highly variable, but also testicular phenotypes range from normal spermatogenesis to complete absence of germ cells.
Birgit Stallmeyer, Ann‐Kristin Dicke, Frank Tüttelmann   +2 more
wiley   +1 more source