Results 41 to 50 of about 193,010 (206)

Pregnancy Rate In Non-Azoospermia With Normal Or Suboptimal Semen Parameter Versus Azoospermic Male Treated By IVF-ICSI Cycle

مجلة الكوفة الطبية, 2023
Background: Intracytoplasmic sperm injection (ICSI) opens the gate for many cases of male factor infertility to be the biological fathers of their sibling since 1992.
Ali A. Abo-Alshaar, Saaduldeen Ghali Al-Esawi, Raghad Hussein Ahmed   +2 more
doaj   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Reinke’s crystals in perivascular and peritubular Leydig cells of men with nonobstructive and obstructive azoospermia: a retrospective case-control study [PDF]

, 2019
Aim To analyze the differences in the population of perivascular and peritubular Leydig cells (LC) and the number of Reinke’s crystals (RCs) in the testicles of infertile men with non-obstructive and obstructive azoospermia.
Di Luca, Monica
core   +1 more source

Sperm retrieval techniques for assisted reproduction

International Brazilian Journal of Urology, 2011
Different surgical methods such as PESA, MESA, TESA, TESE and micro-TESE have been developed to retrieve spermatozoa from either the epididymis or the testis according to the type of azoospermia, i.e., obstructive or non-obstructive.
Sandro C. Esteves, Ricardo Miyaoka, Ashok Agarwal   +2 more
doaj   +1 more source

Serum estradiol levels in infertile men with non-obstructive azoospermia

Therapeutic Advances in Reproductive Health, 2020
Purpose: To report the different patterns of estradiol levels in infertile men with non-obstructive azoospermia and correlate these levels with their clinical and laboratory findings.
Nader Salama, Saeed Blgozah
doaj   +1 more source

Seminal plasma miRNAs in Klinefelter syndrome and in obstructive and non-obstructive azoospermia

, 2020
MicroRNAs are small, non-coding, single-strand oligonucleotides which regulate gene expression. There is little evidence in the literature about their role in azoospermia and no studies have investigated their presence in the seminal plasma of men with ...
Lenzi A., Radicioni A. F., Finocchi F., Pelloni M., Lombardo F., Paoli D., Balercia G., Pallotti F.   +7 more
core   +1 more source

Role of testicular fine‐needle aspiration in the modern male reproductive urologist′s practice

UroPrecision, EarlyView.
Abstract Background Azoospermia affects 10%–15% of infertile men, with non‐obstructive azoospermia (NOA) most often managed by microdissection testicular sperm extraction (mTESE). Despite AUA/ASRM guidelines recommending mTESE, some urologists employ testicular fine‐needle aspiration (TFNA) mapping as a diagnostic adjunct.
Parth Joshi, Jordan Kassab, Vivek Aslot, Richard Schoor   +3 more
wiley   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

A decision analysis of treatments for obstructive azoospermia [PDF]

Human Reproduction, 2008
Treatments for post-vasectomy obstructive azoospermia include vasectomy reversal, microsurgical epididymal sperm aspiration (MESA) or percutaneous testicular sperm extraction (TESE) with IVF/ICSI. We examined the cost-effectiveness of these treatments.A decision analytic model was created to simulate treatment.
R, Lee, P S, Li, M, Goldstein, C, Tanrikut, G, Schattman, P N, Schlegel   +5 more
openaire   +2 more sources

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source