Results 81 to 90 of about 306,427 (235)

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy

JACC: Basic to Translational Science, 2019
Summary: Disopyramide is effective and safe in patients with obstructive hypertrophic cardiomyopathy. However, its cellular and molecular mechanisms of action are unknown.
Raffaele Coppini, MD, PhD, Cecilia Ferrantini, MD, PhD, Josè Manuel Pioner, PhD, Lorenzo Santini, MS, Zhinuo J. Wang, PhD, Chiara Palandri, MS, Marina Scardigli, PhD, Giulia Vitale, MS, Leonardo Sacconi, PhD, Pierluigi Stefàno, MD, Laura Flink, MD, Katherine Riedy, MD, Francesco Saverio Pavone, PhD, Elisabetta Cerbai, PhD, Corrado Poggesi, MD, Alessandro Mugelli, MD, Alfonso Bueno-Orovio, PhD, Iacopo Olivotto, MD, Mark V. Sherrid, MD   +18 more
doaj   +1 more source

Mavacamten safety and efficacy in a heart transplant patient exhibiting obstructive hypertrophic cardiomyopathy phenotype

Hypertrophic cardiomyopathy is the most common inherited cardiac disease, exhibiting diverse phenotypes. Obstructive hypertrophic cardiomyopathy occurs in about two-thirds of cases and carries a worse prognosis.
Tajik, A Jamil, Misicka, Amanda, Abood, Zaid, Ashraf, Muddasir, Peters, Matthew, Galazka, Patrycja, Ghafoor, Asad, Jan, M Fuad, Jahangir, Arshad   +8 more
core   +1 more source

Pregnancy and Cardiomyopathy: A Prospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To establish in a national cohort whether the type of cardiomyopathy in women with a prepregnancy diagnosis affected pregnancy outcomes including mortality, gestational age at birth, and delivery type. Design Prospective Observational study using United Kingdom Obstetric Surveillance System (UKOSS).
Matthew Cauldwell, Mark Johnson, Catherine Nelson Piercy, Philip Steer   +3 more
wiley   +1 more source

Alcohol septal ablation: patient selection and rationality of its application

Патология кровообращения и кардиохирургия, 2017
The article looks at some aspects of selecting patients with obstructive hypertrophic cardiomyopathy for alcohol septal ablation (ASA) procedure. Based on the world’s experience and in the context of evidence-based medicine, the current positions of ASA ...
М. Г. Каштанов, С. Д. Чернышев, Л. В. Кардапольцев, С. В. Бердников, Э. М. Идов   +4 more
doaj   +1 more source

Endocardial septal ablation for hypertrophic obstructive cardiomyopathy

, 2017
Summary– Septal reduction therapy (SRT) is the accepted therapeutic option for symptomatic hypertrophic obstructive cardiomyopathy (HOCM). At this time, surgical septal myectomy is the gold standard method, but alcohol septal ablation is an acceptable ...
Guler, Tumer Erdem, Tümer Erdem Güler, Kazım Serhan Özcan, Kıvanç Yalın, Aksu, Tolga, YALIN, Kıvanç, Ozcan, Kazim Serhan, Şükriye Ebru Gölcük, Golcuk, Sukriye Ebru, Tolga Aksu   +9 more
core   +2 more sources

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Hereditary Transthyretin Cardiac Amyloidosis With Severe Left Ventricular Outflow Tract Obstruction Mimicking Hypertrophic Obstructive Cardiomyopathy

JACC: Case Reports
Background: Cardiac amyloidosis may mimic hypertrophic cardiomyopathy; however, severe left ventricular outflow tract (LVOT) obstruction is rarely described in transthyretin (TTR) cardiac amyloidosis.
Batel Nissan, MD, Nur Magadale, MD, Vladimir Kaplinskiy, MD, Rabea Asleh, MD, PhD, Arthur Pollak, MD, Mordechai Golomb, MD   +5 more
doaj   +1 more source

HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY [PDF]

Heart, 1964
J, COHEN, H, EFFAT, J F, GOODWIN, C M, OAKLEY, R E, STEINER   +4 more
openaire   +2 more sources

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source