Results 61 to 70 of about 102,835 (293)

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad   +9 more
wiley   +1 more source

Evaluation of the Association between Obstructive Sleep Apnea and Hearing Loss

open access: yesJournal of Sleep Sciences, 2016
Background and Objective: Obstructive sleep apnea (OSA) through hypoxia and reoxygenation periods leads to oxidative stress, endothelial dysfunction, and activation of inflammatory cycles, which eventually may cause disorder in vasa nervorum, and ...
Amir Hossein Mohammadi   +4 more
doaj  

Is subjective sleep evaluation a good predictor for obstructive sleep apnea?

open access: yesClinics, 2018
OBJECTIVE: To compare subjective sleep evaluation obtained using four questionnaires with polysomnography results for individuals with and without obstructive sleep apnea.
Cárita de Moura Laranjeira   +2 more
doaj   +1 more source

Hypertension and obstructive sleep apnea

open access: yesNature and Science of Sleep, 2013
Obstructive sleep apnea (OSA) is increasingly being recognized as a major health burden with strong focus on the associated cardiovascular risk. Studies from the last two decades have provided strong evidence for a causal role of OSA in the development of systemic hypertension.
Craig L. Phillips, Denise M. O'Driscoll
openaire   +3 more sources

Atrial fibrillation development in the heart failure population from nationwide British linked electronic health records

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Atrial fibrillation (AF) is a frequent comorbidity in heart failure (HF). We analysed factors associated with new‐onset atrial fibrillation in patients with heart failure using linked real‐world UK data from primary and secondary care, along with findings from genome‐wide association studies. Methods and results Among 163 174 participants
Hiroyuki Yoshimura   +6 more
wiley   +1 more source

A multicentre registry of hospitalized patients with acute and chronic heart failure: Study design of the H2‐registry

open access: yesESC Heart Failure, EarlyView.
The H2‐Registry: overview, first results and outlook. Abstract Aims Heart failure (HF) is a highly prevalent condition affecting 1–3% of the adult population in Europe. Despite landmark improvements in HF care over the last two decades, hospitalization and mortality rates remain relatively high.
Johannes Leiner   +15 more
wiley   +1 more source

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem   +13 more
wiley   +1 more source

Are reduced internal nasal dimensions a risk factor for obstructive sleep apnea syndrome?

open access: yesBrazilian Journal of Otorhinolaryngology, 2022
Introduction: Obstructive sleep apnea syndrome is a high-prevalence disorder found in the population. Studies have shown a possible association between nasal obstruction and obstructive sleep apnea syndrome, but the existence of a association between the
Sergio Henrique Kiemle Trindade   +6 more
doaj  

Arginase activity and nitric oxide levels in patients with obstructive sleep apnea syndrome

open access: yesClinics, 2014
OBJECTIVE: Obstructive sleep apnea syndrome is characterized by repetitive obstruction of the upper airways, and it is a risk factor for cardiovascular diseases.
Meral Yüksel   +4 more
doaj   +1 more source

Exploring heart failure prevalence and dimensions: A comprehensive NT‐proBNP study in high‐risk primary care patients

open access: yesESC Heart Failure, EarlyView.
The diagnostic pathway of high‐risk primary care patients through NT‐proBNP. Abstract Introduction Early detection of heart failure (HF), particularly in asymptomatic individuals, is essential for timely intervention. This study aimed to determine the prevalence of HF among high‐risk individuals in primary care using N‐terminal probrain natriuretic ...
Ahmet Celik   +17 more
wiley   +1 more source

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