Results 51 to 60 of about 1,205 (167)

Real-world evidence of the effectiveness of ombitasvir-paritaprevir/r ± dasabuvir ± ribavirin in patients monoinfected with chronic hepatitis C or coinfected with human immunodeficiency virus-1 in Spain.

PLoS ONE, 2019
AimWe describe the effectiveness and safety of the interferon-free regimen ombitasvir/paritaprevir/ritonavir plus dasabuvir with or without ribavirin (OBV/PTV/r ± DSV ± RBV) in a nationwide representative sample of the hepatitis C virus (HCV ...
José Manuel Sousa, Mercedes Vergara, Federico Pulido, Gloria Sánchez Antolín, Lander Hijona, Fernando Carnicer, Diego Rincón, Javier Salmerón, Beatriz Mateos-Muñoz, Antoni Jou, Benjamín Polo-Lorduy, Ángel Rubín, Ana Escarda, Patricia Aguilar, Teresa Aldámiz-Echevarría, Luisa García-Buey, José A Carrión, Manuel Hernández-Guerra, Sonia Chimeno-Hernández, Nuria Espinosa, Rosa Mª Morillas, Raúl J Andrade, Manuel Delgado, Adolfo Gallego, Marta Magaz, José María Moreno-Planas, Ángel Estébanez, Mikel Rico, Fernando Menéndez, Blanca Sampedro, Luís Morano, Sonia Izquierdo, José Manuel Zozaya, Manuel Rodríguez, Senador Morán-Sánchez, Sara Lorente, Ignacio Martín-Granizo, Miguel Ángel Von-Wichmann, Marcial Delgado, Amanda Manzanares   +39 more
doaj   +1 more source

Influence of shear reinforcement detailing on the shear capacity of reinforced concrete beams

Structural Concrete, EarlyView.
Abstract Alternative shear reinforcement layouts that do not fully enclose the longitudinal tensile reinforcement can significantly improve the constructability of reinforced concrete (RC) members. However, their influence on shear transfer mechanisms is not yet fully understood. To address this gap, an experimental program comprising 10 shear tests on
Franz Untermarzoner, Michael Rath, Simon Leitner, Tobias Huber, Johann Kollegger, Patrick Huber   +5 more
wiley   +1 more source

Arthroscopic Bone Graft Procedure for Anterior Inferior Glenohumeral Instability

Arthroscopy Techniques, 2014
There are many described surgical techniques for the treatment of recurrent anterior shoulder instability. Numerous authors have performed anterior bone block procedures with good results for the treatment of anterior shoulder instability with glenoid ...
Ettore Taverna, M.D., Riccardo D'Ambrosi, M.D., Carlo Perfetti, M.D., Guido Garavaglia, M.D.   +3 more
doaj   +1 more source

Wildfire Ash Alters Freshwater Crustacean Behavior: Disentangling the Contributions of Suspended Macroparticles and Ash‐Induced Alkalinization

Environmental Toxicology, EarlyView.
ABSTRACT Climate change and anthropogenic ignitions are intensifying wildfire frequency worldwide, elevating the risk of freshwater contamination by ash. In water, dissolved ash releases ions and other toxic constituents that increase pH and alter physicochemical conditions, while suspended ash particles may impose mechanical stress, disrupt behavior ...
Pétterson B. Pereira‐Silva, Diogo R. Pacheco, Gustavo Kirsch, Ronnilda M. G. Araujo, Bianca V. C. Oscar, William G. Matias, Sandro Santos, Bruno R. S. Figueiredo   +7 more
wiley   +1 more source

Mosaic chromosomal alterations and relation to haematological cancer in two large Danish cohorts

British Journal of Haematology, EarlyView.
Summary Mosaic chromosomal alterations (mCAs) are large somatic gains, losses and copy‐neutral loss of heterozygosity identified in the peripheral blood, which represent a relatively unexplored spectrum of clonal haematopoiesis. We aimed to describe mCAs in two large Danish cohorts with extensive long‐term registry‐based follow‐up and examine ...
Cecilie Velsoe Maeng, Pei Meng, Mathias Heldbo, Olafur Davidsson, Morten Munk Johansen, Sigrún Thorsteinsdóttir, Jojo Biel‐Nielsen Dietz, Ragnar Pétur Kristjansson, Ole Birger Vesterager Pedersen, Erik Sørensen, Christian Erikstrup, Christina Mikkelsen, Nanna Brøns, Henrik Ullum, Bitten Aagaard, Mie Topholm Bruun, Estrid Høgdall, DBDS Research Consortium, CHB Research Consortium, Bo Porse, Simon Husby, Sisse R. Ostrowski, Henrik Hjalgrim, Kirsten Grønbæk   +23 more
wiley   +1 more source

First experience of off-label use GLE/PIB+SOF in treating a patient with relapse of RNA HCV 1b viremia and RAS R117H in the NS3 region after NS3/4A PI + NS5AI + NS5BI failure of 3D-therapy PTV/R/OBV+DSV in Russia (case report)

HIV Infection and Immunosuppressive Disorders, 2021
For the first time in Russia, a description of a case of full application in clinical practice of a completely interferon-free mode of the 3D-mode GLE/PIB + SOF for the treatment of recurrence of HCV 1b RNA viremia after a primary course of interferonfree therapy in the PTV/r/OBV + DSV mode, which included inhibitors of NS3/4A PI, NS5Ai and NS5Bi, in a
D. L. Sulima, A. A. Yakovlev, V. N. Koryagin, V. A. Larionov, O. V. Gorchakova, E. A. Alekseeva   +5 more
openaire   +2 more sources

Migraine in the cradle of civilization: Evaluating ancient Mesopotamian texts through the lens of ICHD‐3

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Migraine is a neurological disorder with well‐established diagnostic criteria. In its current formulation, migraine is a modern‐day diagnosis, whereas descriptions consistent with migraine may date back to ancient civilizations. Objective This study aimed to investigate whether symptoms consistent with migraine without aura, as ...
Bulent Diri, Bilge Piri Cinar, Zeynep Sena Diri, Okan Bolukbasi, Peter J. Goadsby, Aynur Ozge   +5 more
wiley   +1 more source

Physiological premature aging of ovarian blood vessels leads to decline in fertility in middle-aged mice

Nature Communications
Ovarian function declines significantly as females enter middle-age, but the mechanisms underlying this decline remain unclear. Here, we utilize whole-organ imaging to observe a notable decrease in ovarian blood vessel (oBV) density and angiogenesis ...
Lu Mu, Ge Wang, Xuebing Yang, Jing Liang, Huan Tong, Lingyu Li, Kaiying Geng, Yingnan Bo, Xindi Hu, Ruobing Yang, Xueqiang Xu, Yan Zhang, Hua Zhang   +12 more
doaj   +1 more source

Investor sentiment and stock market returns: A comparative analysis of mood, word, and trade

Journal of Financial Research, EarlyView.
Abstract We examine and compare the return predictability of mood‐, word‐, and trade‐based sentiment measures across 18 international stock markets. Empirical results reveal that the trade‐based measure performs strongly across many settings; the word‐based measure contributes important complementary information, including in cases where the trade ...
Lan Xiang, Wenzhao Wang
wiley   +1 more source

Plasma donation rates and infection risk: A multicentre observational study in Denmark

Vox Sanguinis, EarlyView.
Abstract Background and Objectives The demand for plasma‐derived medicinal products underscores the need to assess health effects of plasma donation. This study examines the association between plasma donation rates and infection risk in a country with voluntary, non‐remunerated donation.
Kathrine Agergård Kaspersen, István Barkos, Lotte Hindhede, Susan Mikkelsen, Khoa Manh Dinh, Nanna Brøns, Jacob Træholt, Christina Mikkelsen, Jakob Thaning Bay, Ole Birger Vesterager Pedersen, Sisse Rye Ostrowski, Erik Sørensen, Bitten Aagaard, Mie Topholm Bruun, Henrik Hjalgrim, Klaus Rostgaard, Henrik Ullum, Erzsébet Horváth‐Puhó, Christian Erikstrup   +18 more
wiley   +1 more source