Results 31 to 40 of about 259 (220)
Neology in children’s literature: A typology of occasionalisms
Lexis: Journal in English Lexicology, 2018 In literature, writers have the liberty to deviate from linguistic norms under a principle known as poetic license. Poetic license allows deviation in favour of making language inspiring.
Cécile Poix
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
ЛЕКСИК ОККАЗИОНАЛИЗМЛАР ВА УНИНГ ЁНДОШ ҲОДИСАЛАРГА МУНОСАБАТИ
Comparative Turkish Dialects and Literatures, 2022 Maqolaning kirish qismida okkazionalizm va neologizm tus-hunchalarining ma'nolari ta'kidlangan. Birinchidan, bu tushunchalarning lug‘atlardagi ma’nolari keltiriladi.
Odina Tuxtasınova
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
MALEBRANCHE DÜŞÜNCESİNDE DİN-FELSEFE İLİŞKİSİ
Fırat Üniversitesi İlahiyat Fakültesi Dergisi, 2014 İnsanın beşeri tecrübe alanlarından ikisini oluşturan din ve felsefe, aynı zamanda sosyal hayatında iki yönünü oluşturmaktadır. Din ve felsefe, bu özelliğinden dolayı da her zaman aralarında bir ilişki bulunmak kaydıyla tarihte yer almıştır.
Haydar Dölek
doaj
SOCIOLECT FORMATION ON THE INTERNET COMMUNICATION
Филологический класс, 2018 In this article, the current problem of the formation of the sociolect of informal Internet communication is considered. As a source of work material, messages from users (non-professionals) from various web-forums are taken.
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source