Results 251 to 260 of about 1,148,117 (381)

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

open access: yesAdvanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li   +10 more
wiley   +1 more source

Experimental Studies on the Coronary Insufficiency and the Cornary Occlusion

open access: bronze, 1957
Eiichi KIMURA   +5 more
openalex   +2 more sources

A Metalloporphyrin Nanosystem Enables Non‐Invasive Visualization and Specific Treatment for Thrombosis and Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
Thrombotic ischemic stroke is a severe neurological disease of the brain that presents major challenges for effective diagnosis and treatment. Precisely engineered Ir and Mn cores within a single porphyrin framework of 4IrMn nanoparticles enable endogenous ONOO−‐ or laser‐activated switching among NIR‐CL imaging, photothermal / photodynamic therapy ...
Ziwei Wang   +10 more
wiley   +1 more source

Soft Micromanipulation Robot for Real‐Time Adaptive Multimodal Operation

open access: yesAdvanced Science, EarlyView.
This manuscript proposes a soft micromanipulator robot (SMR) for “full‐angle” precision biomedical operations. Bio‐inspired SMR achieves omnidirectional motion, micrometer precision, and multimodal capabilities including aspiration, transfer, rotation, assembly, injection, and cutting.
Zhuowei Li   +8 more
wiley   +1 more source

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

open access: yesAdvanced Science, EarlyView.
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley   +1 more source

Contribution of Large Bore Aspiration Catheter to Mechanical Thrombectomy. [PDF]

open access: yesJ Neuroendovasc Ther
Inoue A   +4 more
europepmc   +1 more source

Toward Energy‐Efficient Alkaline Water Electrolysis: Advances in Mass Transport Optimization and Electrolyzer Design

open access: yesAdvanced Energy Materials, EarlyView.
Component‐level engineering in alkaline water electrolysis (AWE) is systematically analyzed, highlighting strategies in porous electrodes, bubble management, membranes, and flow fields to overcome mass‐transport bottlenecks. By linking microstructural design to multi‐scale ionic and gas transport, this Review establishes design principles that connect ...
Qian Zhang   +9 more
wiley   +1 more source

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