Results 261 to 270 of about 833,484 (332)
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang +10 more
wiley +1 more source
Supraceliac aortohepatic bypass for an inferior pancreaticoduodenal artery aneurysm with an associated celiac artery occlusion. [PDF]
Kurzan P +4 more
europepmc +1 more source
“Time Is Brain” – for Cell Therapies
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin +4 more
wiley +1 more source
Primary hyperaldosteronism with bilateral branch retinal vein occlusion as the initial presentation: A case report. [PDF]
Ji X, Mu J, Wang Z, Yang X, Chen C.
europepmc +1 more source
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu +4 more
wiley +1 more source
Comparative outcomes of microsurgical and endovascular treatment for ruptured and unruptured anterior communicating artery aneurysms. [PDF]
Kendirlioglu BC +13 more
europepmc +1 more source
This study highlights the effectiveness of Zn‐induced dendrite layers in enhancing the durability of NiMo HER catalysts under dynamic electrochemical conditions. Through in situ dendritic passivation, the Zn‐NiMo catalyst preserves catalytic active sites and mitigates irreversible Ni oxidation/hydroxylation during repeated load fluctuation.
Taeyoung Jeong +2 more
wiley +1 more source
Subclavian artery stenosis in hemodialysis patients: a case series and review of the literature. [PDF]
Pu W +6 more
europepmc +1 more source
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin +18 more
wiley +1 more source

