Results 21 to 30 of about 377,080 (249)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Acute Effect of Repeated Sprint Exercise With Blood Flow Restriction During Rest Periods on Muscle Oxygenation

Frontiers in Physiology, 2021
PurposeThis study aimed to examine the effect of applying BFR during rest periods of repeated cycling sprints on muscle oxygenation.MethodsSeven active males performed 5 × 10-s maximal pedaling efforts with 40-s passive rest, with or without BFR ...
Chihiro Kojima, Keiichi Yamaguchi, Hiroto Ito, Nobukazu Kasai, Olivier Girard, Kazushige Goto   +5 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Adsorption of Saliva Related Protein on Denture Materials: An X-Ray Photoelectron Spectroscopy and Quartz Crystal Microbalance Study

Advances in Materials Science and Engineering, 2016
The aim of this study was to evaluate the difference in the adsorption behavior of different types of bovine salivary proteins on the PMMA and Ti QCM sensors are fabricated by spin-coating and sputtering onto bare QCM sensors by using QCM and X-ray ...
Akiko Miyake, Satoshi Komasa, Yoshiya Hashimoto, Yutaka Komasa, Joji Okazaki   +4 more
doaj   +1 more source

Ear symptoms in patients with orofacial pain and dysfunction ‐ An explorative study on different TMD symptoms, occlusion and habits

Clinical and Experimental Dental Research, 2021
Objectives Ear symptoms coincident with TMD symptoms have been noticed for a long time. The aim was to investigate the relationship between reported ear symptoms in TMD patients and different TMD symptoms, dental occlusion, oral parafunction and habits ...
Christina Mejersjö, Nina Pauli
doaj   +1 more source

Bilateral retinal artery occlusion; A retrospective analysis of clinical presentation and management

Kerala Journal of Ophthalmology, 2023
Purpose: Retinal artery occlusion (RAO) is an ophthalmologic emergency and involvement of both eyes is rare. The aim of this study was to determine the pattern of presentation of bilateral RAO in south India and the associated systemic disorders. Methods:
Jayant Kumar, Olukorede O Adenuga, Deepesh Chhablani, Haemoglobin Parida, Sabareesh Muraleedharan, Naresh B Kannan, Kim Ramasamy   +6 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Effect of Biological Sex Differences on the Perception of Acute Pain Stimulation in the Dental Setting

Pain Research and Management, 1996
BACKGROUND: Pain is a subjective sensory and emotional experience that is influenced by variables such as stress, anxiety and sex.
Ilana Eli, Yoram Bar-Tal, Zvi Fuss, Ethan Korff   +3 more
doaj   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Application of non-destructive testing methods for assessing fracture resistance in dental ceramics: the sound harvesting test

Frontiers in Dental Medicine
IntroductionEvaluating the fracture resistance of dental ceramics such as monolithic zirconia crowns is crucial for assessing their durability. Conventional destructive laboratory tests often fail to accurately evaluate the timing and failing crack ...
Camille Haddad, Jean Gebran, Amine El Zoghbi   +2 more
doaj   +1 more source