Results 211 to 220 of about 2,220,228 (297)

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol   +4 more
wiley   +1 more source

Possibility of determining high quantitative fecal occult blood on stool surface using hyperspectral imaging. [PDF]

open access: yesJ Gastroenterol
Ikematsu H   +18 more
europepmc   +1 more source

A New Faecal Immunochemical Test Buffer With Improved Haemoglobin Stability Under Varying Temperature and Storage Times

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study investigated faecal haemoglobin (f‐Hb) stability in a new faecal immunochemical test (FIT) buffer formulation, where fresh stool was incubated in buffer under varying temperature and time conditions. Relative to the buffer formulation currently in use (OC‐Sensor SOC3), the new formulation (OC‐Sensor SOC4) could retain more f‐Hb at higher ...
Rafha Rafeeu   +6 more
wiley   +1 more source

Low‐Level Human Epididymis Protein 4 in Seminal Plasma Is an Independent Risk Factor for Poor Semen Liquefaction: A Case Control Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Our work identifies a novel and significant association between low seminal levels of Human Epididymis Protein 4 (HE4) and the clinical condition of poor semen liquefaction, a common cause of male infertility. The findings are statistically robust, clinically relevant, and provide a foundational basis for future research into the mechanism by which HE4
Feifei Wang   +5 more
wiley   +1 more source

Measurements of Liver and Bone Marrow Proton Density Fat Fraction in the Setting of Ferumoxytol‐Enhanced MRI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Proton density fat fraction (PDFF) is typically measured using confounder‐corrected, multi‐echo, gradient‐recalled‐echo chemical‐shift‐encoded (CSE)‐MRI. Ferumoxytol, an iron‐based MRI contrast agent, increases liver and bone marrow (BM) R2*, a major confounder of PDFF.
Lukas Müller   +6 more
wiley   +1 more source

Colorectal Cancer Screening using Immunochemical Faecal Occult Blood Testing (iFOBT) in Urban-Poor Communities in Cheras, Malaysia: A Cross-Sectional Study. [PDF]

open access: yesMalays J Med Sci
Abdul Jalal MI   +15 more
europepmc   +1 more source

Extended Versus Non‐Extended Lymphadenectomy in Radical Cystectomy for Bladder Cancer: A Systematic Review and Meta‐Analysis

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Pelvic lymph node dissection is an essential component of radical cystectomy (RC) for bladder cancer (BC), but the optimal extent of lymphadenectomy remains uncertain. We conducted a systematic review and meta‐analysis to compare oncologic and perioperative outcomes between extended and non‐extended lymphadenectomy during RC for BC.
Maria Fernanda Dias Azevedo   +12 more
wiley   +1 more source

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