Results 1 to 10 of about 63,819 (232)

Viral integration drives multifocal HCC during the occult HBV infection. [PDF]

J Exp Clin Cancer Res, 2019
Although the prognosis of patients with occult hepatitis B virus (HBV) infection (OBI) is usually benign, a small portion may undergo cirrhosis and subsequently hepatocellular carcinoma (HCC).
Chen XP, Long X, Jia WL, Wu HJ, Zhao J, Liang HF, Laurence A, Zhu J, Dong D, Chen Y, Lin L, Xia YD, Li WY, Li GB, Zhao ZK, Wu K, Hou Y, Yu JJ, Xiao W, Wang GP, Zhu PC, Chen W, Bai MZ, Jian YX, Kristiansen K, Chen Q.   +25 more
europepmc   +9 more sources

Occult HBV Infection in Patients Infected by HIV or HCV: Comparison between HBV-DNA and Two Assays for HBsAg [PDF]

Viruses
We investigated the frequency and serological correlates of occult hepatitis B virus infection (OBI) and the potential impact of a highly sensitive assay for HBsAg in subjects infected by human immunodeficiency virus (HIV) or hepatitis C virus (HCV), who
Silvia Meschi, Klizia Mizzoni, Bruno Daniele Leoni, Claudio Galli, Anna Rosa Garbuglia, Stefano Belladonna, Enrico Girardi, Fabrizio Maggi, the HBSAGN Study Group   +8 more
doaj   +3 more sources

Correlation Between the Hepatic Expression of Human MicroRNA hsa-miR-125a-5p and the Progression of Fibrosis in Patients With Overt and Occult HBV Infection [PDF]

Frontiers in Immunology, 2018
AimsTo evaluate the correlation between the hepatic expression pattern of hsa-miR-125a-5p and HBV-DNA and the progression of fibrosis in patients with overt or occult HBV infection.MethodsWe enrolled all the HBsAg-positive treatment naive patients (overt
Nicola Coppola, Nicola Coppola, Lorenzo Onorato, Marta Panella, Giorgio de Stefano, Nicola Mosca, Carmine Minichini, Vincenzo Messina, Nicoletta Potenza, Mario Starace, Loredana Alessio, Nunzia Farella, Evangelista Sagnelli, Aniello Russo   +13 more
doaj   +3 more sources

High-sensitivity HBV DNA test for the diagnosis of occult HBV infection: commonly used but not reliable. [PDF]

Front Cell Infect Microbiol, 2023
Occult hepatitis B virus (HBV) infection (OBI) is a condition in which replication-competent viral DNA is detected in the liver (with detectable or undetectable HBV DNA in serum) of individual testing negative for HBV surface antigen (HBsAg).
Wang C, Xue R, Wang X, Xiao L, Xian J.
europepmc   +2 more sources

The prevalence of occult HBV infection in immunized children with HBsAg-positive parents: a hospital-based analysis. [PDF]

Hepatol Int, 2020
Background and object The risk of occult HBV infection (OBI) in children whose mothers are HBV carriers has received more widespread attention, but there were few reports to focus on the children with HBsAg-positive parents.
Zhuge S, Ge C, Yang Y, Cui Y, Yue X, Zhang Z, Xu H, Huang A, Zhao Y.   +8 more
europepmc   +2 more sources

Reduction of the occurrence of occult HBV infection in infants by increasing the dose of hepatitis B vaccine: a large prospective cohort study. [PDF]

Emerg Microbes Infect, 2020
Occult hepatitis B virus (HBV) infection (OBI) has been observed among infants born to hepatitis B surface antigen (HBsAg)-positive mothers despite successful immunoprophylaxis.
Li AY, Liu Z, Song Y, Xiao Y, Jiang J, Li L, Zhai X, Liu J, Duan Z, Ding F, Liu J, Zhuang H, Zhu L, Jiang J, Zou H, Wang J, Li J.   +16 more
europepmc   +2 more sources

Identification and characteristics of mutations promoting occult HBV infection by ultrasensitive HBsAg assay. [PDF]

J Clin Microbiol
The significance of occult hepatitis B virus (HBV) infection (OBI) has been increasingly recognized while the underlying mechanisms remain incompletely understood.
Song S, Su Q, Yan Y, Ji H, Sun H, Feng K, Nuermaimaiti A, Halemubieke S, Mei L, Liu X, Lu Z, Chang L, Wang L.   +12 more
europepmc   +2 more sources

Nearly half of Ultrio plus NAT non-discriminated reactive blood donors were identified as occult HBV infection in South China. [PDF]

BMC Infect Dis, 2019
BackgroundBlood donor plasma samples were detected by the Ultrio Plus NAT system for HBV, HCV and HIV-1 in Shenzhen blood center, China. Reactive samples underwent further discriminatory testing of a single virus by the same methodology.
Ye X, Li T, Shao W, Zeng J, Hong W, Lu L, Zhu W, Li C, Li T.   +8 more
europepmc   +2 more sources

Occult HBV infection in Chinese blood donors: role of N-glycosylation mutations and amino acid substitutions in S protein transmembrane domains. [PDF]

Emerg Microbes Infect, 2019
Occult hepatitis B virus infection (OBI) is a low-level asymptomatic phase of HBV infection. Evidence of OBI clinical relevance is emerging but the mechanisms of its occurrence remain unclear.
Zhang L, Chang L, Laperche S, Ji H, Zhao J, Jiang X, Wang L, Candotti D.   +7 more
europepmc   +2 more sources

Hepatitis B surface gene variants isolated from blood donors with overt and occult HBV infection in north eastern Egypt [PDF]

Virology Journal, 2015
BackgroundMajor hydrophilic region in genomic HBV extending from aa99 to aa169, clustered with a highly conformational epitope, is critical to the antigenicity of hepatitis B surface antigen (HBsAg) and may affect the diagnosis of HBV in HBV screening ...
Rania M. Kishk, N. Nemr, A. Elkady, Mohamed F. Mandour, M. Aboelmagd, N. Ramsis, M. Hassan, N. Soliman, S. Iijima, S. Murakami, Yasuhito Tanaka, M. Ragheb   +11 more
core   +2 more sources