Results 51 to 60 of about 63,819 (232)

Novel Long‐Read Sequencing Method for Characterisation of Hepatitis B Transcripts Show High Expression of Chimeric HBV/Human RNA

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background Hepatitis B virus (HBV) genomes integrated into human DNA significantly contribute to surface antigen (HBsAg) production and may drive hepatocellular carcinoma (HCC). Long‐read sequencing methods like Nanopore offer advantages over short‐read next‐generation sequencing (NGS) by providing continuous reads of whole transcripts, but ...
Joakim Bedner Stenbäck, Johan Ringlander, Maria Andersson, Jakob Holm Dalsgaard Thomsen, Sanna Abrahamsson, Gustaf E. Rydell, Magnus Lindh   +6 more
wiley   +1 more source

Blood Transfusions: Are They Life Saving or Transfusing Infections? [PDF]

, 2011
Introduction: There is a risk of 1 - 2 per 1000 recipients receiving contaminated blood with viral, bacterial and parasitic agents.TTI’S are the most commonly encountered complications in transfusion medicine.
Amrutha Kumari, B, Deepa, S, Venkatesha, D   +2 more
core   +1 more source

Prevalence and Spectrum of Chronic Liver Disease Among Patients Seeking Health Care in Ghana

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background Chronic liver diseases (CLD) leading to liver fibrosis and cirrhosis are a major cause of morbidity and mortality in sub‐Saharan Africa and pose a significant burden on its health care systems. We aimed to elucidate the prevalence of fibrosis/cirrhosis in patients seeking health care in Kumasi, Ghana, and its underlying aetiologies.
Felix Lehmann, Alexander Killer, Sarah Wels, Stefan Schmiedel, Richard Odame Phillips, Pia Luise Roppert, Kirsten Alexandra Eberhardt, Martha Charlotte Holtfreter, Sabine Stauga, Ansgar Wilhelm Lohse, Stephan Ehrhardt, Ohene Opare‐Sem, Hans Martin Orth, Fred Stephen Sarfo, Christian Drosten, Anna Maria Eis‐Hübinger, Tom Luedde, Dieter Glebe, Jan Felix Drexler, Torsten Feldt   +19 more
wiley   +1 more source

Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection [PDF]

Clinical Infectious Diseases, 2011
Studies of the transmissibility of hepatitis B virus (HBV) in occult hepatitis B (OHB) through blood transfusion are scarce. We aimed to determine the transmissibility of HBV in blood donors with OHB through transfusion in animal and human studies.Among 217,595 blood donors, 67 donors with OHB were identified.
Mizokami, M, Yuen, MF, Wong, DKH, Lee, CK, Tanaka, Y, Allain, JP, Fung, J, Leung, J, Lin, CK, Sugiyama, M, Lai, CL, Sugauchi, F   +11 more
openaire   +4 more sources

Correction to: Occult HBV infection in the oncohematological setting [PDF]

Infection, 2020
n ...
Sagnelli, C., Macera, M., Pisaturo, M., Zampino, R., Coppola, N., Sagnelli, E.   +5 more
openaire   +2 more sources

Indeterminate Phase/Grey Zone of Chronic Hepatitis B: Clinical Features, Outcomes and Molecular Insights

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Chronic hepatitis B virus (HBV) infection remains a global public health challenge, with a high risk of complications such as cirrhosis, hepatocellular carcinoma (HCC) and death. As outlined in current international society guidelines, antiviral therapies are aimed at preventing progression of liver disease to life‐threatening complications ...
Maria Stella Franzè, Teresa Pollicino, Jean‐Michel Pawlotsky, Vincent Leroy, Giovanni Raimondo, Giuliana Amaddeo   +5 more
wiley   +1 more source

Study on methylation level of replication related genes of occult hepatitis B virus

Zhongguo shuxue zazhi, 2022
Objective To study the level of occult hepatitis B virus methylation and replication related genes, and to explore the effect of the former on the latter.
Meilin ZHANG, Ruitao WANG, Shan WANG, Maimaiti HA Limire, Xinjing FU, Lijun ZHOU   +5 more
doaj   +1 more source

Frequency of Anti-HBc & HBV DNA detection in blood donors of Kerman province, Iran

, 2011
Hepatitis B is a serious global infection disease and a major cause of mortality and morbidity worldwide. However, data on Occult Hepatitis B in Iran are scare.
Delavari, Maryam, Owhadi, AR, Renzaho, Andre, Shahabinejhad, Naser, Zahedi, Mujawar   +4 more
core   +1 more source

Hepatitis B serological markers and plasma DNA concentrations. [PDF]

, 2017
OBJECTIVES: To examine hepatitis B (HBV) serological markers and plasma DNA concentrations in a large group of untreated HBV/HIV-coinfected individuals in two sub-Saharan settings. DESIGN: Baseline analysis of a randomized controlled trial. METHODS: DART
Chirara, Michael, DART Virology Group, Dunn, David, Gilks, Charles, Gilson, Richard, Hakim, James, Kaleebu, Pontiano, Kityo, Cissy, Munderi, Paula, Pillay, Deenan, Price, Huw, Spyer, Moira, Vudriko, Tobias, Zachary, Tamale   +13 more
core   +2 more sources

A Quantitative Systems Pharmacology (QSP) Model of Acute Hepatitis B Virus Infection: Mechanistic Insights and Foundations for Future Extensions

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Chronic hepatitis B virus (HBV) infection remains a significant global health challenge. While the dynamic interplay between viral replication and host immune responses determines infection outcomes, the mechanisms driving the resolution of acute infection versus the emergence of chronicity remain incompletely understood.
Clémence Boivin‐Champeaux, Stephan Schmidt, Scott Balsitis, Francine Johansson Azeredo, Justin S. Feigelman   +4 more
wiley   +1 more source