Results 51 to 60 of about 1,649,829 (251)

Serological and Molecular Characterization of Occult HBV Infection in Blood Donors from South Italy

Viruses, 2023
Despite good vaccine coverage and careful blood donor selection policies, hepatitis B virus (HBV) is still the most frequent viral infection among blood donors (BDs) in Italy, mostly in the occult form (OBI). We studied the virological features of OBI in
Alessia Sticchi Damiani, Vera Holzmayer, Claudio Galli, Mariangela De Nuzzo, Mark Anderson, Gavin Cloherty, Nicola Di Renzo   +6 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Prevalence of Occult Hepatitis C Virus Infection in Hemodialysis Patients

Caspian Journal of Internal Medicine, 2021
Background: Via hemodialysis, viral infections can be transmitted in patients a new definition of this infection with no increase in liver enzymes, negative HCV-PCR in serum and presence of virus in the liver and peripheral blood mononuclear cell (PBMC ...
Masomeh Bayani, Mohammad Reza Hasanjani Roushan, Mohammad Jafar Soleimani Amiri, Yousef Yahyapour, Soheil Ebrahimpour, Somayeh Akbarzadeh Jelodar   +5 more
doaj  

Lifestyle factors associated with Occult HCV infection.

, 2018
Lifestyle factors associated with Occult HCV infection.
Luis A. Uribe-Noguez (5287034), María de la Luz Martínez-Rodríguez (5873792), Gamaliel Benitez-Arvizu (5287025), José Antonio Mata-Marin (5287040), María L. Portillo-López (5287028), Carla I. Arroyo-Anduiza (5287037), Alicia Ocaña-Mondragón (5287031)   +6 more
core   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Occult hepatitis B infection by a recombinant D/C virus in an immunosuppressed patient

IDCases, 2020
Approximately 300 million people worldwide were living with chronic hepatitis B virus infection as of 2016, however, this number does not account for those who might be living with occult hepatitis B virus infection due to difficulty diagnosing this ...
Gonçalo Pereira Cruz, Celene Sargento, Maria Conceição Ventura, Joaquim Oliveira, José Saraiva da Cunha   +4 more
doaj   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

A computational approach to identify point mutations associated with occult hepatitis B: significant mutations affect coding regions but not regulative elements of HBV

Virology Journal, 2011
Background Occult Hepatitis B Infection (OBI) is characterized by absence of serum HBsAg and persistence of HBV-DNA in liver tissue, with low to undetectable serum HBV-DNA. The mechanisms underlying OBI remain to be clarified.
Presti Alessandra, Tritarelli Elena, Villano Umbertina, Amadori Alessandra, Marcantonio Cinzia, Prosperi Mattia, Bruni Roberto, Ciccozzi Massimo, Ciccaglione Anna R   +8 more
doaj   +1 more source

Rare detection of occult hepatitis B virus infection in children of mothers with positive hepatitis B surface antigen. [PDF]

PLoS ONE, 2014
The prevalence of occult Hepatitis B virus (HBV) infection in children was considerably varied from 0.1-64% in different reports. In this study we aimed to investigate the prevalence of occult HBV infection among the children born to mothers with ...
Yong Liu, Jian Wen, Jie Chen, Chenyu Xu, Yali Hu, Yi-Hua Zhou   +5 more
doaj   +1 more source

Occult infection in pseudarthrosis revision after spinal fusion [PDF]

, 2020
BACKGROUND CONTEXT Pseudarthrosis after attempted spinal fusion is yet not sufficiently understood and presents a surgical challenge. Occult infections are sometimes observed in patients with pseudarthrosis and no inflammatory signs of infection.
Betz, Michael, Farshad, Mazda, Burkhard, Marco D, Bauer, David E, Uçkay, Ilker, Loretz, Ruben   +5 more
core   +1 more source