Results 61 to 70 of about 1,649,829 (251)

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

Advanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld, C. L. Dietsche, F‐L. Born, I. Onipko, L. Blaase, P. S. Dittrich   +5 more
wiley   +1 more source

Occult hepatitis B virus infection and its demographic and clinical determinants among blood donors in Saudi Arabia: A retrospective cross-sectional study

Journal of International Medical Research
Objective Occult hepatitis B virus infection, characterized by the presence of hepatitis B virus DNA in the absence of detectable hepatitis B surface antigen, poses a significant risk to blood donation safety. This study aimed to determine the prevalence
Abdulrahman F Alrezaihi, Lama Alzamil, Abdulrahman Alshalani, Jawaher Alsughayyir, Fahad S Alshehri, Abdulaziz M Almuqrin   +5 more
doaj   +1 more source

Serological pattern of anti-HBc alone infers occult hepatitis B virus infection in high-risk individuals in Iran

, 2010
Introduction: Anti-hepatitis B core antibody (Anti-HBc) alone is defined as the presence of anti-HBc in the absence of HBsAg and anti-HBs. The significance of this serological pattern as a predicting factor for occult hepatitis B virus (HBV) infection ...
Mohammad Banifazl, Ali Eslamifar, Amitis Ramezani, Arezoo Aghakhani   +3 more
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Occult hepatitis B infection and its possible impact on chronic hepatitis C virus infection

The Saudi Journal of Gastroenterology, 2009
As a well-recognized clinical phenomenon, persistent detectable viral genome in liver or sera in the absence of other serological markers for active hepatitis B virus (HBV) replication is called occult HBV infection.
Habibollahi Peiman, Safari Saeid, Daryani Nasser, Alavian Seyed   +3 more
doaj  

THE PROBLEMS OF PROVIDING INFECTIOUS DISEASE SAFETY FOR ORGAN AND TISSUE DONATION BY SCREENING BLOOD-BORNE VIRAL INFECTIONS

Вестник трансплантологии и искусственных органов, 2016
It provided data on the prevalence, clinical signifi cance and methods of laboratory diagnostics for occult forms of blood-borne viral infections (BBVIs).
M. Sh. Khubutiya, S. A. Solonin, M. A. Godkov   +2 more
doaj   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source

Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection [PDF]

, 2005
Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality.
Dunn, C., Maini, M.K., Copas, A., Gilson, R.J., Lascar, R.M., Johnstone, R., Bertoletti, A., Webster, G., Lopes, A.R., Reignat, S.   +9 more
core  

Hepatitis B virus infection among sexually active individuals in Nigeria: a cross-sectional study

The Pan African Medical Journal, 2018
INTRODUCTION: Hepatitis B virus (HBV) infection is a major health challenge in sub-Saharan African countries. Chronic HBV infection is a risk factor for severe disease progression.
Yewande Nejo, Adedayo Omotayo Faneye, Babatunde Olusola, Solomon Bakarey, Adebowale Olayinka, Babatunde Motayo, PERVI Study Group   +6 more
doaj   +1 more source