Results 21 to 30 of about 669,107 (251)

Lung injury induced by different negative suction pressure in patients with pneumoconiosis undergoing whole lung lavage

open access: yesBMC Pulmonary Medicine, 2022
Background Pneumoconiosis is a diffuse interstitial fibronodular lung disease, which is caused by the inhalation of crystalline silica. Whole lung lavage (WLL) is a therapeutic procedure used to treat pneumoconiosis.
Mingyuan Yang   +7 more
doaj   +1 more source

Autophagy-dependent lysosomal calcium overload and the ATP5B-regulated lysosomes-mitochondria calcium transmission induce liver insulin resistance under perfluorooctane sulfonate exposure

open access: yesEcotoxicology and Environmental Safety
Perfluorooctane sulfonate (PFOS), an officially listed persistent organic pollutant, is a widely distributed perfluoroalkyl substance. Epidemiological studies have shown that PFOS is intimately linked to the occurrence of insulin resistance (IR). However,
Jixun Li   +8 more
doaj   +1 more source

Airborne Levels of Lung Carcinogens at an Ascon Manufacturing Site

open access: yesAerosol and Air Quality Research, 2020
We assessed the airborne concentrations of the dust (both total and respirable), quartz, polycyclic aromatic hydrocarbons, and elemental carbon in an ascon manufacturing environment to determine the exposure to operators and the likelihood of developing ...
Kyeongmin Lee   +4 more
doaj   +1 more source

hgweon/occupation-coding v1.0.0

open access: yes, 2017
R codes for occupation ...
hgweon
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Translating and Standardizing the Persian Version Measure of Process of Care for Service Providers (MPOC-SP) in Down Syndrome [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2019
Background & Objective: Down syndrome is the most common type of chromosomal abnormality that causes mental disability. In recent years, the life expectancy of these children has increased, so their special needs will also increase.
sahar sadeghi   +4 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Challenges of teaching occupation: introduction of an occupation focused teaching tool [PDF]

open access: yes, 2017
Occupational science is of importance to multiple disciplines due to its potential to contribute to understandings of complex social issues. “Occupation”, as a key concept of occupational science, is recognised as being highly complex, making it ...
Karen Morris   +7 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Lysosomal iron accumulation and subsequent lysosomes-mitochondria iron transmission mediate PFOS-induced hepatocyte ferroptosis

open access: yesEcotoxicology and Environmental Safety
Perfluorooctane sulfonate (PFOS) is known as a persistent organic pollutant. A significant correlation between PFOS and liver ferroptosis has been unveiled, but the precise mechanism needs to be elucidated. In prior research, we found that PFOS treatment
Jixun Li   +9 more
doaj   +1 more source

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