Results 81 to 90 of about 9,733,946 (330)

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Meta-analysis of dose-response relationship between body mass index and low back pain in Chinese occupational population

环境与职业医学
BackgroundLow back pain is one of the most common types of work-related musculoskeletal disorders (WMSDs). There are no consistent results on the relationship between body mass index (BMI) and low back pain in available research.ObjectiveTo explore the ...
Lihua DING, Kangkang ZHANG, Jiabing WU, Yan YAO, Ruijie LING, Fei LIU   +5 more
doaj   +1 more source

Occupational Pesticide Exposure, Impaired DNA Repair, and Diseases

Indian Journal of Occupational and Environmental Medicine, 2018
Pesticides are a mixture of chemical substances used to kill pests. Apart from their toxicity to pests, thy affect nontarget organisms. They also generate free radicals producing reactive oxygen species (ROS) which can disturb cellular pathways by ...
Karashdeep Kaur, R. Kaur
semanticscholar   +1 more source

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

Advanced Science, EarlyView.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan, Xiaolong Liu, Qiming Xia, Guoqiao Chen, Jiaxi Cheng, Zhaoqi Shi, Yifeng Fang, Parikshit Asutosh Khadaroo, Jun Qian, Hui Lin   +9 more
wiley   +1 more source

Japanese Guideline for Occupational Allergic Diseases 2014

Allergology International, 2014
In 2013, a guideline for occupational allergic diseases was published for the first time in Japan. Occupational allergic diseases are likely to worsen or become intractable as a result of continuous exposure to high concentrations of causative antigens ...
Kunio Dobashi, Kazuo Akiyama, Atsushi Usami, Hiroo Yokozeki, Zenro Ikezawa, Naomi Tsurikisawa, Yoichi Nakamura, Kazuhiro Sato, Jiro Okumura   +8 more
doaj   +1 more source

Novel Role of Gut‐Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure

Advanced Science, EarlyView.
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou, Chunsong Wang, Jieying Gao, Xu Wu, Geng Li, Xuejun Jiang, Yinyin Xia, Jun Zhang, Bo Lv, Feng Zhao, Hongyang Zhang, Huifeng Pi, Jingfu Qiu, Shangcheng Xu, Zhen Zou, Chengzhi Chen   +15 more
wiley   +1 more source

INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASE

, 1920
Emery R. Hayhurst, E. B. Starr
  +9 more sources

Occupational stress and associated factors among couriers: A Cross-Sectional study

BMC Public Health
Background In all spheres of life, occupational stress has steadily emerged as a major influence on people's physiology and psychology. There is currently little research on couriers as a high-risk group for occupational stress. Objective This study aims
Dexiang Zhu, Ruyun Bai, Meiqiong Guo, Liuzhuo Zhang, Xizhi Wang, Dafeng Lin, Shaofan Weng, Ming Zhang, Naixing Zhang   +8 more
doaj   +1 more source

Analysis of newly diagnosed occupational diseases in Yangzhou from 2012 to 2022

Zhiye weisheng yu yingji jiuyuan
: Objective To understand the incidence characteristics, changing trends, and patterns of occupational diseases in Yangzhou, clarify the key areas for prevention and control of occupational disease, and provide a basis for formulating city-wide ...
LI Xiaoqin
doaj   +1 more source

Japanese guidelines for occupational allergic diseases 2017

Allergology International, 2017
In 2013, a guideline for occupational allergic diseases was published for the first time in Japan. Occupational allergic diseases are likely to worsen or become intractable as a result of continuous exposure to high concentrations of causative antigens ...
Kunio Dobashi, Kazuo Akiyama, Atsushi Usami, Hiroo Yokozeki, Zenro Ikezawa, Naomi Tsurikisawa, Yoichi Nakamura, Kazuhiro Sato, Jiro Okumura, Kaoru Takayama   +9 more
doaj   +1 more source