Results 71 to 80 of about 2,709,547 (312)

Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

open access: yesAdvanced Science, EarlyView.
Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley   +1 more source

Assignment of chemical exposure parameter in occupational health risk assessment models: Key consideration

open access: yes环境与职业医学
The core idea of occupational health risk assessment models is to systematically evaluate occupational health risks according to target hazard characteristics and relevant exposure levels of workers.
Jiayun DING   +4 more
doaj   +1 more source

Latex anaphylaxis in healthcare worker and the occupational health management perspective: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Latex allergy is a critical occupational health problem in healthcare settings. Exposure to latex can lead to severe allergic reactions, including anaphylaxis.
Chatpong Ngamchokwathana   +1 more
doaj   +1 more source

Occupational noise exposure: A review of its effects, epidemiology, and impact with recommendations for reducing its burden.

open access: yesJournal of the Acoustical Society of America, 2019
Exposure to hazardous noise is one of the most common occupational risks, both in the U.S. and worldwide. Repeated overexposure to noise at or above 85 dBA can cause permanent hearing loss, tinnitus, and difficulty understanding speech in noise.
C. Themann, Elizabeth A Masterson
semanticscholar   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

open access: yesAdvanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang   +13 more
wiley   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan   +12 more
wiley   +1 more source

OCCUPATIONAL ACCIDENTS WITH BIOLOGICAL MATERIAL AMONG HEALTHCARE WORKERS

open access: yesCogitare Enfermagem, 2017
The present study aimed at characterizing occupational accidents with biological material among healthcare workers. A retrospective, quantitative study of accidents involving biological material, conducted in a secondary reference hospital located in the
Manoel Carlos Arantes   +5 more
doaj   +1 more source

Interior Decorative VOCs Elevate T Cell‐Mediated Obstructive Lung Disease Risks via Osteogenesis‐Driven Lymphoid‐Biased Hematopoiesis

open access: yesAdvanced Science, EarlyView.
This study utilizes a whole‐body inhalation model to reveal that interior decorative VOCs exposure persistently elevates alveolar T cells. This increase is attributed to lymphoid‐biased hematopoiesis in the bone marrow, which is further driven by IL‐6/IL‐17A‐mediated osteogenic differentiation.
Hongyan Yu   +11 more
wiley   +1 more source

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