Results 101 to 110 of about 2,742,526 (343)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Antiferromagnetism and Superconductivity in a Model with Extended Pairing Interactions

, 2001
The competition between antiferromagnetism and the $d+id$ superconducting state is studied in a model with near and next near neighbour interactions in the absence of any on-site repulsion.
Beck, H., Maitra, Tulika, Taraphder, A.
core   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Comparative Statics on Asset Prices Based on Bull and Bear Market Measure [PDF]

For single-period complete financial asset markets with representative investors, we introduce a bull market measure for uncertain state occurrence and its associated ordering between representative investors in markets based on their marginal rate of ...
Masamitsu Ohnishi, Yusuke Osaki
core  

Fuzzy modeling of the risk of cacao moniliasis occurrence in Bahia state, Brazil [PDF]

, 2020
Samira Luns Hatum de Almeida, Samuel de Assis Silva, Julião Soares de Souza Lima, Jorge Tadeu Fim Rosas, Vinícius Agnolette Capelini   +4 more
openalex   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Variation characteristics of CO2 adsorption phase density in coal seam and Its Controlling mechanism: A case study of Huainan-Huaibei coalfield

Meitian dizhi yu kantan
Objectives and Methods The CO2 adsorption phase density is a key factor determining the CO2 adsorption sequestration capacity in coal seams. To deeply understand the characteristics of CO2 density distribution in pores of the coal seam, taking the No.13 ...
Huihu LIU, Zhengpu FAN, Jinghao YANG, Junlin LIU, Hai DING, Hongjie XU, Deyi GAO, Huihuang FANG, Yuqing ZHAO   +8 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Fractal Characteristics of Pore Structure in Lacustrine Shale Oil Reservoirs and Controlling Factors of Oil Occurrence State: A Case Study of Da’anzhai Member, Sichuan Basin

Fractal and Fractional
The Jurassic lacustrine oil shale in southwest China has become a primary production layer due to its high yield and substantial reserves. However, influenced by the lacustrine environment, the vertical profile of the lacustrine shale reservoir shows ...
Miao Li, Xueying Yan, Yuqiang Jiang, Hongzhan Zhuang, Zhanlei Wang   +4 more
doaj   +1 more source