Results 101 to 110 of about 19,107,119 (264)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Quantitative Assessment of Free and Adsorbed Shale Oil in Kerogen Pores Using Molecular Dynamics Simulations and Experiment Characterization

open access: yesEnergies
Understanding the microscopic occurrence states of shale oil—particularly the distribution between adsorbed and free phases—is essential for optimizing the development of unconventional reservoirs. In this study, we propose an integrated methodology that
Yuhao Guo   +7 more
doaj   +1 more source

New electronic state documents list - January 2024

open access: yes
The monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Study on occurrence law of sulfur in high-sulfur coal with different particle sizes and densities

open access: yesMeikuang Anquan
To investigate the state of sulfur in different particle sizes and density fractions of high-sulfur coal, the Ciyaogou high-sulfur coal was divided into particle size and density fractions according to the screening method and flotation method.
Yulong YANG, Fei GAO, Yunming ZHANG
doaj   +1 more source

New electronic state documents list -February 2024

open access: yes
The monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core  

Report of the State Irrigation Commissioner to the Kansas State Board of Agriculture, 1924-26

open access: yes, 1926
WATER COMMISSION, KANSAS -- “The Kansas Water Commission was created by an Act of Legislature in 1917 for the purpose of investigating and controlling the problems of flood prevention, drainage, domestic water supply, water power, navigation and ...
Kansas. State Irrigation Commissioner
core  

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Distribution State of Zinc and the Rare Elements Gallium and Germanium in a Zinc Ore

open access: yesKuangchan zonghe liyong
This is an article in the field of process mineralogy. The occurrence of zinc, associated dispersed elements Ga and Ge and the distribution characteristics of the main carrier minerals of a zinc ore in China are studied in detail by means of chemical ...
Lili ZHANG   +5 more
doaj   +1 more source

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