Results 231 to 240 of about 393,547 (305)

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

Seasonal Predictions and Their Applications in the Mediterranean Region: Part I—Sources of Predictability and Prediction Skill

open access: yesInternational Journal of Climatology, EarlyView.
The ability to predict climate fluctuations at seasonal timescales offers significant socio‐economic benefits. However, limited understanding of predictability mechanisms and model errors hinders forecast quality. Recent research has improved forecasting systems and data quality.
Gualdi Silvio   +12 more
wiley   +1 more source

Evapotranspiration Profiles and Trends in Seasonally Dry and Seasonally Humid Tropical Forests

open access: yesInternational Journal of Climatology, EarlyView.
Moisture availability and vegetation are decisive factors in ET variations, which are greater in the Atlantic Forest. Precipitation contributes positively to ET variations (r = 0.20–0.67). Significant trends (p < 0.05) in ET were identified, with opposing patterns.
Lucas de Morais Teixeira   +5 more
wiley   +1 more source

Compound Hot‐Dry Days (CHDDs) and Their Implications on Maize Yields in the Free State Province, South Africa

open access: yesInternational Journal of Climatology, EarlyView.
Compound hot‐dry events occurring during the maize growing period are increasing significantly (p < 0.05) with time, with the median values ranging from 93 to 120 days. El Niño Southern Oscillation (ENSO) influences the variability of compound hot‐dry events with high significance (p < 0.05) positive Pearson correlation.
Mokhele Moeletsi, Mitsuru Tsubo
wiley   +1 more source

Evaluation of CMIP6 Models in Simulating Australian Monsoon Over Northern Australia

open access: yesInternational Journal of Climatology, EarlyView.
The study assesses CMIP6 models for their ability to simulate key aspects of the Australian summer monsoon, including precipitation patterns, wind circulation, monsoon onset/retreat, and ENSO teleconnections. Most models overestimate rainfall, underestimate wind strength, and simulate more uniform ENSO influence across northeast and northwest Australia.
Rida S. Kiani   +4 more
wiley   +1 more source

Mapping the Spatial Scales of Australian Extreme Precipitation Using Daily Rain Gauges

open access: yesInternational Journal of Climatology, EarlyView.
We present the first continent‐wide analysis of the spatial scales of daily extreme precipitation events (EPEs) in Australia using station observations and semivariogram analysis. EPEs generally have larger spatial scales at higher latitudes, with strong seasonal and regional differences shaped by topography, meteorological regimes, and climate ...
Dongqi Lin   +2 more
wiley   +1 more source

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