Results 61 to 70 of about 7,656 (257)

Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming

Advanced Science, EarlyView.
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai, Zhiying Yang, Zongguang Liu, Wanjia Hu, Lixiao Ma, Enze Kang, Wanqing Luo, Yunpeng Zhao, Chengzhu Liu, Juan Jia, Ting Liu, Chen He, Quan Shi, Jianliang Liu, Yongheng Gao, Huai Chen, Hailong Zhang, Meixun Zhao, Xiaojuan Feng   +18 more
wiley   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Ship-Based Contributions to Global Ocean, Weather, and Climate Observing Systems

Frontiers in Marine Science, 2019
The role ships play in atmospheric, oceanic, and biogeochemical observations is described with a focus on measurements made near the ocean surface. Ships include merchant and research vessels; cruise liners and ferries; fishing vessels; coast guard ...
Shawn R. Smith, Gaël Alory, Axel Andersson, William Asher, Alex Baker, David I. Berry, Kyla Drushka, Darin Figurskey, Eric Freeman, Paul Holthus, Tim Jickells, Henry Kleta, Elizabeth C. Kent, Nicolas Kolodziejczyk, Martin Kramp, Zoe Loh, Paul Poli, Ute Schuster, Emma Steventon, Sebastiaan Swart, Sebastiaan Swart, Oksana Tarasova, Loic Petit de la Villéon, Nadya Vinogradova-Shiffer   +23 more
doaj   +1 more source

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

A Modular PLUG‐IN Photosynthetic Chassis With Tunable Thermal Control for Mammalian Systems

Advanced Science, EarlyView.
This work establishes a “plug‐in” chassis compatible with mammalian systems that synchronizes growth, production, and cell‐wall re‐configuration, providing a versatile platform for photosynthetic bioproduction and microalgal synthetic biology. ABSTRACT Microalgae are promising photosynthetic platforms for high‐value compounds, yet their industrial use ...
Qinhua Gan, Zheng Li, Yunfei Chen, Mingting Du, Qianyi Wu, Congcong Miao, Tao Xu, Shan Wu, Xitao Chen, Xingwei Huang, Yuhui Cheng, Chengcheng Li, Yi Xin, Yandu Lu   +13 more
wiley   +1 more source

Efficient Concentration and Complete Destruction of Short‐Chain and Emerging PFAS in Contaminated Water via Integrated Interface Engineering‐Enhanced Carbon Felt Sorption and Photochemical Processes

Advanced Science, EarlyView.
A closed‐loop “Concentrate‐Destroy” strategy is presented for completely eliminating short‐chain and emerging PFAS, in which the new 3D PPy@P‐CF is used for efficiently concentrating PFAS and Cu2+‐mediated photodegradation is applied for the completely destroying PFAS in the sorbent regeneration eluent.
Hao Yu, Jialei Guo, Peng Zhang, Hongyi Li, Feng He, Hongwen Sun   +5 more
wiley   +1 more source

Multidisciplinary Observing in the World Ocean’s Oxygen Minimum Zone Regions: From Climate to Fish — The VOICE Initiative

Frontiers in Marine Science, 2019
Multidisciplinary ocean observing activities provide critical ocean information to satisfy ever-changing socioeconomic needs and require coordinated implementation.
Véronique Garçon, Johannes Karstensen, Artur Palacz, Maciej Telszewski, Tony Aparco Lara, Denise Breitburg, Francisco Chavez, Paulo Coelho, Marcela Cornejo-D’Ottone, Carmen Santos, Björn Fiedler, Natalya D. Gallo, Natalya D. Gallo, Marilaure Grégoire, Dimitri Gutierrez, Dimitri Gutierrez, Martin Hernandez-Ayon, Kirsten Isensee, Tony Koslow, Lisa Levin, Lisa Levin, Francis Marsac, Helmut Maske, Baye C. Mbaye, Ivonne Montes, Wajih Naqvi, Jay Pearlman, Edwin Pinto, Grant Pitcher, Grant Pitcher, Oscar Pizarro, Oscar Pizarro, Kenneth Rose, Damodar Shenoy, Anja Van der Plas, Melo R. Vito, Kevin Weng   +36 more
doaj   +1 more source

Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates

Advanced Science, EarlyView.
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao, Yufei Liu, Ruixi Huang, Zhongxue Gan, Siyang Leng   +4 more
wiley   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

From Observation to Information and Users: The Copernicus Marine Service Perspective

Frontiers in Marine Science, 2019
The Copernicus Marine Environment Monitoring Service (CMEMS) provides regular and systematic reference information on the physical and biogeochemical ocean and sea-ice state for the global ocean and the European regional seas.
Pierre Yves Le Traon, Antonio Reppucci, Enrique Alvarez Fanjul, Lotfi Aouf, Arno Behrens, Maria Belmonte, Abderrahim Bentamy, Laurent Bertino, Vittorio Ernesto Brando, Matilde Brandt Kreiner, Mounir Benkiran, Thierry Carval, Stefania A. Ciliberti, Hervé Claustre, Emanuela Clementi, Giovanni Coppini, Gianpiero Cossarini, Marta De Alfonso Alonso-Muñoyerro, Anne Delamarche, Gerald Dibarboure, Frode Dinessen, Marie Drevillon, Yann Drillet, Yannice Faugere, Vicente Fernández, Andrew Fleming, M. Isabel Garcia-Hermosa, Marcos García Sotillo, Gilles Garric, Florent Gasparin, Cedric Giordan, Marion Gehlen, Marilaure L. Gregoire, Stephanie Guinehut, Mathieu Hamon, Chris Harris, Fabrice Hernandez, Fabrice Hernandez, Jørgen B. Hinkler, Jacob Hoyer, Juha Karvonen, Susan Kay, Robert King, Thomas Lavergne, Benedicte Lemieux-Dudon, Leonardo Lima, Chongyuan Mao, Matthew J. Martin, Simona Masina, Angelique Melet, Bruno Buongiorno Nardelli, Glenn Nolan, Ananda Pascual, Jenny Pistoia, Atanas Palazov, Jean Francois Piolle, Marie Isabelle Pujol, Anne Christine Pequignet, Elisaveta Peneva, Begoña Pérez Gómez, Loic Petit de la Villeon, Nadia Pinardi, Andrea Pisano, Sylvie Pouliquen, Rebecca Reid, Elisabeth Remy, Rosalia Santoleri, John Siddorn, Jun She, Joanna Staneva, Ad Stoffelen, Marina Tonani, Luc Vandenbulcke, Karina von Schuckmann, Gianluca Volpe, Cecilie Wettre, Anna Zacharioudaki   +76 more
doaj   +1 more source