Results 41 to 50 of about 101,034 (228)
EBioMedicine, 2019 Background: Whether achieving sustained virological response (SVR) in patients with hepatitis C attains complete elimination of hepatitis C virus (HCV) is unknown, because occult HCV infection (OCI), defined as the detection of HCV-RNA in hepatocytes or ...
Yijin Wang +12 more
doaj +1 more source
Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia [PDF]
, 2015 Approximately 20% of patients with acute myeloid leukaemia (AML) have a mutation in FMS-like-tyrosine-kinase-3 (FLT3). FLT3 is a trans-membrane receptor with a tyrosine kinase domain which, when activated, initiates a cascade of phosphorylated proteins ...
A Puissant +49 more
core +2 more sources
Chiari I Malformation: Review and Update of Current Treatment Options
Clinical Anatomy, EarlyView.ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo +11 more
wiley +1 more source
The NPM1 wild-type OCI-AML2 and the NPM1-mutated OCI-AML3 cell lines carry DNMT3A mutations [PDF]
Leukemia, 2011 The NPM1 wild-type OCI-AML2 and the NPM1 -mutated OCI-AML3 cell lines carry DNMT3A ...
TIACCI, Enrico +7 more
openaire +3 more sources
European Eating Disorders Review, EarlyView.ABSTRACT Objective Maladaptive exercise is a common symptom of eating disorders (EDs). While several measures exist to assess current maladaptive exercise, there are no validated self‐report tools to assess maladaptive exercise history—an important symptom domain among individuals with lifetime EDs.
Katherine Schaumberg +23 more
wiley +1 more source
Non-perturbative Gauge Groups and Local Mirror Symmetry [PDF]
, 2001 We analyze D-brane states and their central charges on the resolution of C^2/Z_n by using local mirror symmetry. There is a point in the moduli space where all n(n-1)/2 branches of the principal component of the discriminant locus coincide. We argue that
Skarke, H.
core +2 more sources
Generalized OCI schemes for boundary layer problems [PDF]
Mathematics of Computation, 1980 A family of tridiagonal formally fourth-order difference schemes is developed for a class of singular perturbation problems. These schemes have no cell Reynolds number limitation and satisfy a discrete maximum principle. Error estimates and numerical results for this family of methods are given, and are compared with those for several other schemes.
Alan E. Berger +4 more
openaire +1 more source
European Eating Disorders Review, EarlyView.ABSTRACT Objective Although obsessive‐compulsive disorder (OCD) commonly co‐occurs with anorexia nervosa and bulimia nervosa, less is known about its relationship with avoidant/restrictive food intake disorder (ARFID) dimensions. Whether associations between ARFID dimensions and OCD differ by sex is also unclear.
Mariana Valdez Aguilar +15 more
wiley +1 more source
European Eating Disorders Review, EarlyView.ABSTRACT Background For adolescents with Anorexia Nervosa (AN) or Atypical Anorexia Nervosa (AAN), Family Based Treatment (FBT) is an effective treatment. However, outcomes remain suboptimal, making investigations into predictors of outcome important. Most prior research into FBT has focussed on parental and family factors as predictors.
Daniel Wilson +7 more
wiley +1 more source
JIMD Reports, 2019 Fabry disease (FD) patients may suffer from objective cognitive impairment (OCI). This study assessed the accuracy of the Mini Mental State Examination (MMSE) to screen for OCI in FD patients.
Simon Körver +5 more
doaj +1 more source