Results 81 to 90 of about 2,884,168 (334)
Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging [Invited].
Biomedical Optics Express, 2017 In vivo imaging of the human retina with a resolution that allows visualization of cellular structures has proven to be essential to broaden our knowledge about the physiology of this precious and very complex neural tissue that enables the first steps ...
M. Pircher, R. Zawadzki
semanticscholar +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Beyond backscattering: Optical neuroimaging by BRAD
, 2018 Optical coherence tomography (OCT) is a powerful technology for rapid volumetric imaging in biomedicine. The bright field imaging approach of conventional OCT systems is based on the detection of directly backscattered light, thereby waiving the wealth ...
Augustin, Marco +11 more
core +1 more source
Biomedical Optics Express, 2017 Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of non-invasive and non-contact imaging by detecting back-scattered light.
J. D. de Boer, R. Leitgeb, M. Wojtkowski
semanticscholar +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Design and implementation of a low-cost, portable OCT system.
Biomedical Optics Express, 2018 Optical coherence tomography (OCT) is a widely used biomedical imaging tool, primarily in ophthalmology to diagnose and stage retinal diseases. In order to increase access for a wider range of applications and in low resource settings, we developed a ...
Sanghoon Kim +5 more
semanticscholar +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Current and Future Advanced Imaging Modalities for the Diagnosis of Early Osteoarthritis of the Hip
Orthopedic Research and Reviews, 2022 Emily S Mills,1 Jacob A Becerra,1 Katie Yensen,1 Ioanna K Bolia,1 Edward C Shontz,1 Kareem J Kebaish,1 Andrew Dobitsch,1 Laith K Hasan,1 Aryan Haratian,1 Charlton D Ong,2 Jordan Gross,2 Frank A Petrigliano,1 Alexander E Weber1 1Department of Orthopaedic ...
Mills ES +12 more
doaj
Biomedical Optics Express, 2017 25 years is a relatively short period of time for a medical technology to become a standard of care impacting the treatment of millions of people every year.
E. Swanson, J. Fujimoto
semanticscholar +1 more source